The General Hospital Corporation

Walfre Franco

William A Farinelli

R Rox Anderson

Joshua Tam

Martin Purschke

Apostolos G Doukas

Fernanda Hidemi Sakamoto

Min Yao

Warren M Zapol

Luca Zazzeron

Joel N Jimenez-Lozano

Richard Rox Anderson

Esmeralda Ibarra-silva

Lynn A Drake

Anna Fischbach

Lynn Drake

Ying Wang

Richard A Anderson

Sandeep Korupolu

Richard R Anderson

William F Farinelli

Rox R Anderson

Exemplary methods and devices can be provided for harvesting a plurality of small tissue pieces, e.g., having widths less than about 1 mm or 0.5 mm, using one or more hollow needles. A fluid can be flowed through a conduit past the proximal ends of the needles to facilitate removal of the tissue pieces from the needle lumens, and can maintain the tissue pieces in a controlled and protective liquid environment. A filter can be used to extract and collect the tissue pieces from the liquid, or the tissue pieces can be deposited directly onto a porous dressing. Such tissue pieces can be used as microscopic grafts, which can be applied directly to a wound site or provided on a substrate or dressing, or stored for later use. Such microscopic grafts can promote tissue regrowth and wound healing, or can be applied to a scaffold to grow new tissue.

Method and apparatus for tissue harvesting

Systems and methods are provided for performing a hair transplant using a hair transplant device. The hair transplant device comprises an extraction unit including a coring needle configured to extract at least one hair follicle from a donor site, an implanting unit removably coupled to the extraction unit, the implanting unit including a splitting needle configured to create an opening in a recipient site, a housing coupled to the extraction unit, and a user interface extending from the housing and moveable relative to the housing. The user interface includes a pin movable within the coring needle relative to the housing.

Systems and methods for a hair transplant system with extraction and implantation needles

Systems and methods are provided for performing a hair transplant using a hair transplant device. The hair transplant device comprises a coring needle, a splitting needle, a housing, and a user interface. The coring needle forms a coring lumen configured to extract a hair follicle from a donor site. The splitting needle is configured to create an opening in a recipient site. The housing at least partially surrounds one of the coring needle and the splitting needle. The user interface extends from the housing and is movable relative to the coring needle to push the hair follicle from the coring lumen into the opening in the recipient site formed by the splitting needle.

Systems and methods for hair transplant

Systems and methods for removing carbon monoxide from whole blood are provided. In one configuration, an extracorporeal phototherapy system includes an oxygenator and a light source configured to output light and arranged to emit the light output by the light source onto at least one surface of the oxygenator. The oxygenator includes a plurality of membrane layers each having a plurality of microporous hollow fiber membranes. The plurality of microporous hollow fiber membranes each include an external surface and an internal channel. Each of the plurality of membrane layers may be rotationally offset with respect to an adjacent layer. The oxygenator further includes a gas inlet port in fluid communication with a first end of the internal channels, a gas outlet port in fluid communication a second end of the internal channels, a blood inlet port, and a blood outlet port.

System and method for extracorporeal carbon monoxide removal with phototherapy

Exemplary embodiments of apparatus and method for obtaining one or more portions of biological tissue ('micrografts') to form grafts are provided. For example, a hollow tube can be inserted into tissue at a donor site, and a pin provided within the tube can facilitate controlled removal of the micrograft from the tube. Micrografts can be harvested and directly implanted into an overlying biocompatible matrix through coordinated motion of the tube and pin. A needle can be provided around the tube to facilitate a direct implantation of a micrograft into a remote recipient site or matrix. The exemplary apparatus can include a plurality of such tubes and pins for simultaneous harvesting and/or implanting of a plurality of micrografts. The harvested micrografts can have a small dimension, e.g., less than about 1 mm, which can promote healing of the donor site and/or viability of the harvested tissue.

Method and apparatus for tissue grafting and copying

Systems and methods are provided for treating or preventing carbon monoxide poisoning. In particular, systems and methods are provided for a phototherapy treatment or prevention system that delivers light radiation to a patient's body to photodissociate carbon monoxide from hemoglobin.

System and method for phototherapy for preventing or treating carbon monoxide poisoning

The present disclosure relates to exemplary embodiments of method and apparatus for harvesting, handling and implanting small tissue grafts obtained from a donor site. In some embodiments the apparatus includes hollow needles and base that can be formed of one or more biocompatible materials that are biodegradable and/or dissolvable.

Method and apparatus for tissue copying and grafting

Systems and methods for assembling a plurality of tissue grafts are provided. A method includes harvesting the plurality of micro tissue grafts from a donor site, arranging the plurality of micro tissue grafts in a desired orientation, forming a tissue construct containing the plurality of micro tissue grafts arranged in the desired orientation, and applying the tissue construct to a recipient site.

Growing community of inventors

Worcester, MA, United States of America

Walfre Franco