King Abdulaziz University

Waleed Rizg

Raed Felimban

Hossam H Tayeb

Tarek Abdelnapy Ahmed

Khalid Mohamed El-Say

Fuad Alnadwi

Abdelsattar Mansour Omar

Ashraf B Abdel-Naim

Osama A A Ahmed

Nabil Abdulhafiz Alhakamy

Usama Ahmed Fahmy

Hani Zakariah Asfour

Adeel Chaudhary

Jwana Bin Mahfouz

Fuad H AlNadwi

Nojod Hasaballah

Majed Felemban

A nano-pharmaceutical formulation, comprising zein nanoparticles, icariin (ICA) or a pharmaceutically acceptable salt thereof encapsulated within the zein nanoparticles, at least one solubilizer, wherein the at least one solubilizer comprises D-a-Tocopherol polyethylene glycol 1000 succinate (TPGS), and one or more pharmaceutical penetration enhancers is provided. Methods of enhancing libido by administering a composition as described herein is also provided.

Icariin nano-pharmaceutical formulation

An oil-in-water nanoemulsion is provided. The nanoemulsion contains 8-12% w/v essential oil, 1-5% w/v polysorbate 80 surfactant, 2-6% w/v glyceryl citrate/lactate/linoleate/oleate co-surfactant, and 1-5% w/v glycerol monocaprylate, type I, wherein a ratio of the surfactant and co-surfactant to essential oil is from 1:1.1 to 1:1.6. Methods of preparing the nanoemulsion and for the transdermal delivery of the nanoemulsion are also provided.

Essential oil nanoemulsion and methods of use thereof

Provided are a self-nanoemulsifying 3D printer ink composition and a method of using such composition to manufacture a 3D-printed tablet having compartmentalized active pharmaceutical ingredients. In particular, the 3D-printed tablet composition includes glimepiride and/or rosuvastatin in a curcuma oil based self-nanoemulsifying drug delivery system (SNEDDS). The disclosure also provides a method of treating a metabolic disorder or disease by administering a therapeutically effective amount of the 3D-printed tablet to a subject in need thereof.

Methods for treating metabolic disorder

Provided are a self-nanoemulsifying 3D printer ink composition and a method of using such composition to manufacture a 3D-printed tablet having compartmentalized active pharmaceutical ingredients. In particular, the 3D-printed tablet composition includes glimepiride and/or rosuvastatin in aoil based self-nanoemulsifying drug delivery system (SNEDDS).

Self-nanoemulsifying 3D-printed tablet composition and method of use thereof

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Jeddah, Saudi Arabia

Waleed Rizg