Life Technologies Corporation

Sherwood Services Ag

Wade Lukianow

Michael J Lands

Robert Setterquist

Randel Alven Frazier

Timothy Barta

Alexandre Vlassov

Robert Smith

Justin Inslee

Ethan Gentert

Jason Jones

Sara Thiele

Jay Greco

Christopher Crowley

Sandro David Klein

Syrus Jaffe

Marie Gonzalez

Eric Liu

Christopher Martin

Carolyn Johnson

John Staton

Carolyn Adams

Anne Cox

Mark Mayernick

Allan Evans

Andrew Basta

Brian Vajda

Sumonto Ghosh

David Cerrone

Kraig Kruger

Laboratory instrument

Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Systems, methods, and devices for automated nucleic acid and protein isolation

A endoscopic bipolar forceps for clamping and sealing tissue includes first and second jaw members pivotally attached in opposing relation relative to one another which are movable from a first open position wherein the jaw members are disposed in spaced relation relative to one another to a second clamping position wherein the jaw members cooperate to grasp tissue therebetween. A drive rod assembly connects each of the jaw members to a source of electrical energy such that the jaw members are capable of conducting bipolar energy through the tissue held therebetween. A handle attached to the drive rod assembly imparts movement of the first and second jaw members from the first and second positions. At least one stop member is attached to the jaw members for controlling the distance between the jaw members. The forceps may also include a yoke member for insulating the jaw members from one another to prevent short circuiting of the forceps. Preferably, the yoke member and jaw member interface is dimensioned to withstand the high shearing forces normally associated with sealing tissue.

Endoscopic bipolar electrosurgical forceps

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Boulder, CO, United States of America

Wade Lukianow