University of Manitoba

Diamedica Inc.

Scimar Ltd.

W Wayne Lautt

Helen Wang

Paula Macedo

Y Luke Zhang

The present invention provides methods of treating prediabetes, hyperglycemia, type 2 diabetes, AMIS syndrome, and obesity in a subject by administering to the patient HISS. The present invention also provides methods of diagnosing AMIS syndrome in a patient. Additionally, the present invention provides a method of shifting nutrient storage in meat-producing livestock to muscle rather than fat.

Hepatic insulin sensitizing substance and test meal for insulin sensitization

There is provided a method of reducing insulin resistance in a mammalian patient comprising selecting a patient suffering from insulin resistance and administering a compound which increases hepatic glutathione and a compound which increases hepatic nitric oxide.

Use of glutathione synthesis stimulating compounds in reducing insulin resistance

A method is provided for increasing insulin responsiveness and improving glucose tolerance in a mammal comprising administration of an effective amount of a cholinergic agonist; pharmaceutical compositions are also provided.

Growing community of inventors

Winnipeg, Canada

W Wayne Lautt