Other

Columbia University

W Louis Cleveland

Y Lawrence Yao

Xi Long

The present invention provides for a method of treating OCD or an Obsessive-Compulsive Spectrum Disorder (OCSD), such as BDD or ADHD, using a high-dose glycine treatment.

High-dose glycine as a treatment for obsessive-compulsive disorder and obsessive-compulsive spectrum disorders

High dose glycine as a treatment for obsessive-compulsive disorder and obsessive compulsive spectrum disorders

A method of identifying and localizing objects belonging to one of three or more classes, includes deriving vectors, each being mapped to one of the objects, where each of the vectors is an element of an N-dimensional space. The method includes training an ensemble of binary classifiers with a CISS technique, using an ECOC technique. For each object corresponding to a class, the method includes calculating a probability that the associated vector belongs to a particular class, using an ECOC probability estimation technique. In another embodiment, increased detection accuracy is achieved by using images obtained with different contrast methods. A nonlinear dimensional reduction technique, Kernel PCA, was employed to extract features from the multi-contrast composite image. The Kernel PCA preprocessing shows improvements over traditional linear PCA preprocessing possibly due to its ability to capture high-order, nonlinear correlations in the high dimensional image space.

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New York, NY, United States of America

W Louis Cleveland