University of Sharjah

Vunnam Srinivasulu

Taleb H Altel

Hany A Omar

Farah Ibrahim Al-Marzooq

Amin Majdalawieh

Amjad Ali

Saleh Ibrahim

Paul Schilf

Mawieh Hamad

Mohamad Hamad

Shifaa Abdin

Imad Abu Yousef

The present invention relates to novel antitumor agents and pharmaceutically acceptable salts thereof, processes and intermediates for the manufacture of these novel constrained cyclic frameworks of general formula I and II, and medicaments containing such compounds.

Discovery of novel first in class nature-inspired compounds targeting the mitochondrial function and pharmaceutical composition thereof

There is provided novel anticancer and antibacterial compounds, pharmaceutically acceptable salts thereof, and processes for their preparation. The compounds have anticancer activity, which results in the reduction of tumour cell proliferation, enhances cancers cells apoptosis and regulation of iron signalling. The compounds are also particularly active against various Gram-negative and Gram-positive multidrug-resistant bacteria, such as extended-spectrum beta-lactamase (ESBL) producing and colistin-resistant, carbapenem-resistant, carbapenem-resistant, and methicillin-resistant(MRSA) including those with reduced susceptibility to many control antibiotics.

Nature-inspired anticancer and antibacterial motifs and pharmaceutical composition thereof

Growing community of inventors

Sharjah, United Arab Emirates

Vunnam Srinivasulu