Medimmune Limited

Aridis Pharmaceuticals

Medimmune Vaccines, Inc.

University of Colorado

Medlmmune Limited

Vu Truong-Le

Binh Pham

Satoshi Ohtake

Luisa Yee

Russell E Martin

David Lechuga-Ballesteros

Theodore W Randolph

John Frank Carpenter

Palani Balu

Atul Saxena

Robert Seid

George Robert Trager

Harshvardhan Mehta

Tom Scherer

Eric Tsao

Binh V Pham

Russell Martin

Richard M Schwartz

Alfred A Pan

Chiaoyin Kathy Wang

Zhongying Chen

A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such asspecies,as well as those caused by, and multidrug resistant, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.

Gallium formulation for the treatment and prevention of infectious diseases

A method for the selection of pharmaceutically acceptable excipients that allow for the production of highly dispersible powders produced by spray drying.

Highly dispersible powders, compositions and methods for preparation

Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided.

Methods of producing influenza vaccine compositions

This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles.

Sonic low pressure spray drying

This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes.

Preservation of bioactive materials by freeze dried foam

This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles.

Spray freeze dry of compositions for pulmonary administration

This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.

Preservation of bioactive materials by spray drying

This invention provides formulations and methods for stabilizing viruses in liquid and dried formulations. In particular, formulations are provided including Zn+ cations that stabilize the viability of Rotaviruses. Methods of vaccination include neutralization of gastric contents and administration of the vaccine formulations of the invention.

Formulations for preservation of rotavirus

Growing community of inventors

Campbell, CA, United States of America

Vu Truong-Le