Julius-Maximilians-Universitat Wurzburg

Other

Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt

Volker Christian Behr

Martin Rueckert

Patrick Vogel

Martin Rückert

Thomas Kampf

A system for generating a traveling field free line, traveling along a propagation direction different from the orientation of said traveling field free line, said system comprising at least a first and a second coil assembly, wherein said first coil assembly is configured for generating a first stationary field free line at a first location when a current is flowing in the first coil assembly and the second coil assembly is current free, and wherein said second coil assembly is configured for generating a second stationary field free line at a second location, when a current is flowing in the second coil assembly and the first coil assembly is current free. The system further comprises a controller configured for driving the first and second coil assemblies with corresponding driving currents synchronized with each other, such that said traveling field free line travels along the propagation direction from a first location towards a second location.

System and method for generating a traveling field free line

The invention relates to a method for determining the presence of an analyte by means of a distribution of small magnetic particles. According to said method, the magnetizations of the small particles are oriented in relation to each other by means of an outer magnetic focusing field; once the focussing field has been terminated, the magnetizations of the small particles are rotated asynchronously to the magnetic field by means of an outer magnetic field of suitable field intensity and rotational frequency, which rotates about a longitudinal axis (z); the temporal course of the superpositioned transverse magnetization of the set of particles is detected; and the presence of the analyte is deduced from the detected temporal course. The invention also relates to a corresponding device ().

Method for determining the presence of an analyte by means of small magnetic particles, and corresponding device

The invention relates to a method for imaging from a distribution of small magnetic particles. According to said method, the magnetisation of the small particles is rotated asynchronously to the magnetic field by means of an outer magnetic field of suitable field intensity and rotational frequency, which rotates about a longitudinal axis (z), whereby an asynchronous average rotational frequency is generated for a set of particles according to the field intensity; a spatial dependence is impressed on each set of particles by means of a magnetic gradient field of the asynchronous average rotational frequency; the frequency parts of the superpositioned transverse magnetisation (MQ) of the set of particles are detected; and a spatially resolved distribution of the transverse magnetisation (MQ) determines the small particles and emits same by means of the frequency parts. The invention also relates to a suitable device (). An improved spatial resolution can be obtained, compared to the previous magnetic particle imaging methods, with essentially lower field intensities.

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Gerbrunn, Germany

Volker Christian Behr