University of Utah Research Foundation

Vladimir Y Panin

Gengsheng Lawrence Zeng

Grant T Gullberg

A method of constructing a non-uniform attenuation map ( ) of a subject for use in image reconstruction of SPECT data is provided. It includes collecting a population of a priori transmission images and storing them in an a priori image memory ( ). The transmission images not of the subject. Next, a cross-correlation matrix ( ) is generated from the population of transmission images. The eigenvectors ( ) of the cross-correlation matrix ( ) are calculated. A set of orthonormal basis vectors ( ) is generated from the eigenvectors ( ). A linear combination of the basis vectors ( ) is constructed ( ), and coefficients for the basis vectors are determined ( ) such that the linear combination thereof defines the non-uniform attenuation map ( ).

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Salt Lake City, UT, United States of America

Vladimir Y Panin