Essilor International (compagnie Generale D'optique)

Transitions Optical, Inc.

Vladimir Lokshin

Robert Guglielmetti

Andre Samat

Karine Chamontin

Jean L Pozzo

Pierre Lareginie

Elena Zaballos Garcia

Guena Elle Harie

Andr E Samat

Homoazaadamantane spirooxazines and their use in the field of ophthalmic

The new photochromic compounds according to the invention, of the spiro[indoline-[2,3']-benzoxazine] type, include at least one electron-withdrawing group attached to the benzoxazine structure in 5' or 6' position by a chain containing at least one ethylenic double bond. Application to ophthalmic optics.

Photochromic spirooxazine compounds, their use in the field of

Photochromic compounds and methods for their use

The invention concerns photochromic compounds with general formula (I): ##STR1## where R.sup.a, R.sup.b and R.sup.c represent hydrogen; alkyl, aryl, OR, SR, COR or COOR, where R represents hydrogen, alkyl or aryl, amino with formula NR.sub.1 R.sub.2, where R.sub.1 and R.sub.2 each represent hydrogen, alkyl, cycloalkyl, or aryl, R.sub.1 and R.sub.2 may together form a heterocycle containing four to seven members with the nitrogen atom and may intracyclically contain one or more heteroatoms selected from nitrogen, oxygen, sulphur, or a halogen atom; a mono- or polyhaloalkyl; an NO.sub.2, CN or SCN group; n and m represent whole numbers from 1 to 4 depending on the number of substitutions on the nucleus and p is 1 or 2 depending on the number of substitutions on the nucleus; H is either an aromatic heterocycle condensed at the 5,6 or 6,7 positions, containing five or six members comprising one or more heteroatoms selected from nitrogen, selenium, oxygen and sulphur or an aromatic carbocycle containing five or six members, condensed at the 7,8 positions; all optionally substituted. The invention also relates to the use of these compounds in ophthalmic optics.

Ring spiro [fluorene-[2H]-benzopyranes] and their use in ophthalmic

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Marseille, France

Vladimir Lokshin