Other

Arzneimittelwerk Dresden Gmbh

Vladimir G Granik

Mikhail D Mashkovsky

Robert G Glushkov

Irina A Ivanova

Jury G Bobkov

Antonina I Polezhaeva

Alexandr S Losev

Roza B Parimbetova

Lidia F Roschina

Tatyana V Stezhko

Hans-Joachim Lankau

Klaus Unverferth

Reni Bartsch

Thomas Arnold

Sofia Grizik

Abgelika Rostock

Antiepileptic compounds of the formula ##STR1## wherein X is hydrogen, a C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, trifluoromethoxy or halogen residue, A is an amino, C.sub.1-4 alkylamino, C.sub.1-4 dialkylamino, morpholino, piperidino or pyrrolidino residue, and n is a cardinal number from 0 to 5, and process for preparing the foregoing compounds and for their use as anticonvulsives.

4-amino-1-arylpyridin-2-ones and process for making

A novel compound, namely, 1-thiocarbamylmethylpyrrolidine-2-thione has the following formula: ##STR1## A process for preparing said compound comprises reacting a derivative of pyrrolidone-2 of the general formula: ##STR2## wherein R is nitrile or carbamoyl, with phosphorus pentasulphide in an inert non-polar solvent at a temperature above room temperature, followed by treatment of the resulting precipitate with water upon boiling and isolation of the desired product. The compound according to the present invention exhibits antihypoxic and nootropic activity.

1-thiocarbamylmethylpyrrolidine-2-thione, process for preparing

1-Thiocarbamoylmethylpyrrolidine-2-thione, medical compositions of, and

Growing community of inventors

Moscow, Russia

Vladimir G Granik