Institut Neftekhimicheskogo Sinteza Imeni A.v.topchieva Rossiiskoi

Orex Pharmaceutical Development Corp.

Vladimir Alexnadrovich Knyazhev

Lev I Valuev

Nikolai Alfredovich Plate

Tatyana Alexandrovna Valueva

Jay M Henis

Ljudmila Konstantinovna Staroseltseva

Alexander S Ametov

Alexandr Sergeevich Ametov

Ludmila K Staroseltseva

A therapeutic-containing composition adapted for the oral administration of a biologically active material which comprises a water insoluble but water swellable polymer chemically modified with an enzyme inhibitor containing a chemical functionality which has an interactive affinity for target receptors located on the transport barrier walls of the digestive tract of the intended recipient, and at least one therapeutic of low oral bioavailability.

Protein-containing polymer composition for oral administration

An insulin-containing polymer composition intended for the oral administration of insulin, which comprises a hydrophilic polymer modified with an inhibitor of proteolytic enzyme, insulin and water, wherein the inhibitor of proteolytic enzymes is ovomucoid isolated from duck or turkey egg whites.

Insulin-containing polymer composition for oral administration

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Moscow, Russia

Vladimir Alexnadrovich Knyazhev