Regeneron Pharmaceuticals, Inc.

Galera Labs, LLC

Emisphere Technologies, Inc.

Vivien Wong

David M Rothstein

Chris Murphy

Glenn Kazo

Ehud Arbit

Michael M Goldberg

Richat Abbas

Neil E Stahl

Donald J Sarubbi

Steven Minh Dinh

Nikos Panayotatos

David J Glass

Mark E Furth

Friedrich Lottspeich

Nancy Y Ip

Hans Thoenen

Piotr J Masiakowski

Gregory Conn

Kurt Stockli-Rippstein

Dan B Lindholm

Georg W Kreutzberg

Michael Sendtner

Yoshihiro Arakawa

Patrick Desmond Carroll

Rudolf Georg Gotz

Ellen M Koehler-Stec

T Cooper Woods

Michael Goldberg

Methods and kits for treating oral mucositis are disclosed. The treatment comprises administering to a patient in need thereof a Reactive Oxygen Species scavenger in a pharmaceutically acceptable formulation.

Methods of treating oral mucositis

An oral dosage form comprises cromolyn sodium (sodium or disodium cromoglycate), and an acylated amino acid delivery agent.

Formulations for oral administration of cromolyn sodium

Pharmaceutical dosage forms for oral administration to a patient for the treatment of diabetes, comprising insulin and a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and that result in a lower incidence of vascular diseases associated with the repeated administration of insulin are disclosed. Also disclosed is a method of attenuating the undesirable incidence of diseases associated with chronic dosing of insulin is provided whereby the oral administration to a patient of insulin along with a suitable delivery agent that facilitates the absorption of insulin from the gastrointestinal tract of the patient in a therapeutically effective amount, for treatment of diabetes.

Oral insulin therapy

Compositions and methods for the intranasal or respiratory administration of ciliary neurotrophic factor proteins, especially in the treatment of obesity and gestational or adult onset diabetes.

Use of ciliary neurotrophic factor

DNA encoding human ciliary neurotrophic factor and method for producing the protein encoded thereby

The present invention provides for a method of promoting motor neuron survival, growth or differentiation comprising treating motor neurons with an effective amount of HGF. The invention also provides for a method of promoting motor neuron survival, growth or differentiation comprising treating motor neurons with an effective amount of HGF and an effective amount of CNTF. The invention further provides for a method of alleviating the toxic effects of vincristine on motor neurons comprising treating motor neurons with an effective amount of HGF and an effective amount of CNTF. The methods may be carried out in vitro or in vivo. The invention also provides a method of treating a motor neuron disorder in a patient comprising administering to the patient an effective amount of HGF and CNTF. The invention further provides a pharmaceutical composition for treating a motor neuron disorder in a patient comprising HGF and CNTF in a pharmacologically acceptable carrier.

Methods of using hepatocyte growth factor to promote survival, growth

Growing community of inventors

Scarsdale, NY, United States of America

Vivien Wong