Biolipox Ab

Galleon Pharmaceuticals, Inc.

Neurad Ltd.

Latvian Institute of Organic Synthesis

Vita Ozola

Edgars Suna

Scott L Dax

Benjamin Pelcman

Ivars Kalvins

James Joseph Mencel

Martins Katkevics

Kirill Shubin

Kristofer Olofsson

Aigars Jirgensons

Ilona Domracheva

Dace Katkevica

Marina Martjuga

Peteris Trapencieris

Wesley Schaal

Gundars Leitis

Iveta Kanepe-Lapsa

Kristaps Jaudzems

Linda Kinena

The present invention includes compounds that are useful in the prevention and/or treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of preventing and/or treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound and/or composition of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound and/or composition of the invention.

Breathing control modulating compounds, and methods of making and using same

The present invention includes pyrimido[5,4-d]pyrimidines that are useful in the prevention and/or treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of preventing and/or treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention.

Breathing control modulating compounds, and methods of using same

 There is provided compounds of formula (I), wherein X, Q, T, Y, R, R, R, Rand Rhave meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

Indoles useful in the treatment of inflammation

There is provided a compound of formula: (I), wherein X, R, R, R, R, Rand Rhave meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation. 

Growing community of inventors

Adazu nov., Latvia

Vita Ozola