Synthezyme, LLC

Vishal Shah

Richard A Gross

Gustavo F Doncel

Datta Madamwars

Frantisek Nerud

A method for producing sophorolipids having protein inducer and/or repressor activities having the steps of synthesizing the sophorolipid by fermentation ofin a fermentation media to form a natural mixture of lactonic sophorolipids and non-lactonic sophorolipids and then utilizing the natural mixture as a protein inducing agent, utilizing the natural mixture as a protein repressing agent, and/or utilizing the natural mixture as a combined protein induction/repressor agent. An application of the sophorolipid compound produced according to the method as a microbial media component.

Sophorolipids as protein inducers and inhibitors in fermentation medium

17-L-[(2'-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octa-decenoate, lactonic and open ring 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, methyl 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, hexyl 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6&#x2033;-acetate and ethyl 17-L-[(2&#x2032;-O-&#x3b2;-D-glucopyranosyl-&#x3b2;-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6&#x2032;,6&#x2033;-diacetate sophorolipids and uses thereof as antifungal agents.

Method for neutralizing fungi using sophorolipids and antifungal sophorolipids for use therein

A method for neutralizing or inactivating a virus, and neutralizing or inactivating HIV using sophorolipids having antiviral properties produced by synthesizing the sophorolipid by fermentation ofin a fermentation media to form a natural mixture of lactonic sophorolipids compounds and non-lactonic sophorolipids compounds and utilizing the natural mixture as an antiviral agent, and/or separating the lactonic sophorolipids from the natural mixture to form a lactonic fraction and mixing all remaining fractions to form a non-lactonic fraction and utilizing the lactonic fraction and/or the non-lactonic fraction as an antiviral agent, and sophorolipid compounds for use as antiviral agents.

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Oakdale, NY, United States of America

Vishal Shah