University of Pennsylvania

Rohm and Haas Company

Virgil Percec

Anatoliy V Popov

Daniela A Wilson

Christopher J Wilson

Tamaz Guliashvili

Andrew Edward Feiring

Antony Keith Van Dyk

Brad Matthew Rosen

Sven Fleischmann

Susan Jane Fitzwater

Andrew D Hughes

Pawaret Leowanawat

Alex Asandei

Firouz Asgarzadeh

SET-LRP polymerization of acrylic monomers under acidic conditions is described. The source of the acidity may be the solvent (e.g., an acetic acid-containing solvent) or in the monomer content (e.g., acrylic acid or methacrylic acid, optionally in combination with other monomers such as methyl methacrylate).

Set-LRP polymerization of acrylates in the presence of acids

The invention concerns compounds of the formula (I) wherein: Yand Yare independently a monosaccharide or disaccharide; Xand Xare independently &#x2014;(R&#x2014;O)&#x2014;, &#x2014;(R)&#x2014;, &#x2014;O&#x2014;(R&#x2014;O)&#x2014;, &#x2014;R&#x2014;O&#x2014;R&#x2014;O&#x2014; or a covalent bond; Qand Qare independently a nitrogen-containing heterocycle moiety; Zand Zare independently &#x2014;(O&#x2014;R)&#x2014;, &#x2014;(O&#x2014;C(&#x2550;O)&#x2014;R)a-, &#x2014;O&#x2014;C(&#x2550;O)&#x2014;R&#x2014;C(=0)-R&#x2014;, &#x2014;O&#x2014;C(&#x2550;O)&#x2014;R&#x2014;C(&#x2550;O)&#x2014;Ror a covalent bond; R-Rare each independently C-Calkyl; R-Rare each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6. 

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes

The invention concerns compounds of the formula: X&#x2014;(Y)wherein: X is Formula (X), each Y is the same or different and is Formula (Y) &#x2014;O&#x2014;[CH&#x2014;CH(OH)&#x2014;CH&#x2014;O&#x2014;]&#x2014;H; or &#x2014;C(OR); R, R, R, R, R, R, R, Rare each, independently, &#x2014;(CHCHO)&#x2014;R, &#x2014;[CHCH(OH)CHO]H, OR, &#x2014;O(CH)R, or &#x2014;(CH)R; each Ris independently ORor OH; R, Rand Rare each, independently, H or C-Calkyl; Ris &#x2014;NHClor &#x2014;NHBoc; t is an integer from 2 to 6; m, n, and p are each, independently, an integer from 1 to 12; and each q, r, and s is 0 or 1 and the sum of q+r+s is at least 2. 

Amphiphilic Janus-dendrimers

The present invention concerns the design of an environmentally friendly and efficient fluorous phase based on dendritic architectures containing short semifluorinated groups on their periphery.

Fluorous dendrimers and methods for production thereof

The invention concerns processes for the synthesis of a compound of the formula: wherein: Rand Rare each, independently, C-Calkyl, COR, OR, R(OR), or C-Caryl; R-Rare each, independently, C-Calkyl or C-Caryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:&#x2014;contacting a compound of the formula H0-R-0H with BHand a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where Ris a C-Chydrocarbon group and X is a halogen, OMs or OTs;&#x2014;contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen. 

Processes for the preparation of biphenyl compounds

The invention concerns a method of polymerizing an alkene monomer to produce a polymer using a catalyst that is Cu(O), CuTe, CuSe, CuS, CuO, or a combination thereof, an initiator, and a component comprising a solvent and optional nitrogen-containing ligand, where the combination of the component and monomer is capable of diproportionating Cu(I)X into Cu(O) and Cu(II)Xwhere X is Cl, Br, or I.

Living radical polymerization of activated and nonactivated monomers containing electron-withdrawing side groups

The inventive subject matter relates to novel synthetic processes which use a multifunctional compound (the 'TERMINI compound') having a masked or protected functional group, wherein the TERMINI compound is capable of quantitatively and irreversibly interrupting a living polymerization or a chain organic reaction. After deprotection or demasking of the functional group of the TERMINI compound, the same living polymerization or organic reaction resumes with 100% efficiency, or a different living polymerization or organic reaction resumes with 100% chemoselectivity, respectively. Once incorporated into a growing molecule, the TERMINI compound generates a branching point upon resumption of the polymerization or reaction.

Processes for the synthesis of dentritic macromolecules from conventional monomers

An amphiphilic dendritic dipeptide, comprises a dipeptide(s) comprising one or more of a naturally occurring or synthetic amino acids and a dendron. These are suitable for use in various formulations, films, coatings, membranes and sensors, among other applications.

Amphiphilic dendritic dipeptides and their self-assembly into helical pores

Acrylic polymers are made by the living radical polymerization of acrylic monomers utilizing organo halide initiators with either metal-free or metal catalysts. Moreover, block copolymers of vinyl halide monomers and acrylic monomers are described by generally polymerizing either the vinyl halide monomers or acrylic monomers utilizing an organo halide initiator in the presence of either a metal catalyst or a metal-free catalyst and subsequently polymerizing thereon the remaining type of monomer.

Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom

Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom

A living polymerization process for preparation of poly(vinyl chloride) (PVC) with controlled molecular weight and molecular weight distribution is described. The polymerization reaction can be initiated by various polyhalocarbon initiators in conjunction with non-metallic reducing single electron transfer reagents as catalysts and accelerated by electron shuttles. The process occurs at room temperature in water or water-organic solvent medium. The polymerization provides PVC with a controlled molecular weight and narrow molecular weight distribution. The halogen containing polymer compositions are useful as, among others, viscosity modifiers, impact modifiers and compatibilizers.

Aqueous room temperature living radical polymerization of vinyl halides

A process for the preparation of polyvinyl chloride (PVC) with controlled molecular weight and molecular weight distribution is disclosed. The polymerization reaction can be initiated by various organic halide initiators in conjunction with a metal catalyst and an optional ligand in organic solvents or water and in the presence of an optional comonomer. The polymerization process provides PVC with a controlled molecular weight and narrow molecular weight distribution. The chlorine containing polymers compositions are useful as, among others, viscosity modifiers, impact modifiers and compatibilizers.

Process for the living radical polymerization of chlorine containing monomers

This invention relates to novel fluorinated dendrons and to a universal strategy for producing functional fluorinated dendrons programmed to self-assemble into supramolecular nanocylinder compositions containing p-stacks of high electron or hole mobility donors (D), acceptors (A), or D-A complexes in the core. Such nanocylinder compositions are uniquely applicable to devices spanning from single supramolecule to nanoscopic and to macroscopic scales including transistors, photovoltaics, photoconductors, photorefractives, light emissives, and optoelectronics.

Fluorinated dendrons and self-organizing ultrahigh density nanocylinder compositions

A graft copolymer composition and the preparation of the composition by living radical polymerization is disclosed. The polymerization reaction can be initiated at active chlorine sites on the poly(vinyl chloride) backbone in conjunction with a transition metal catalyst and an optional ligand. The graft copolymers are useful as, among others, compatibilizers for blends and alloys, as high heat distortion temperature poly(vinyl chloride) materials, as impact modifiers, and permanently plasticized materials.

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Philadelphia, PA, United States of America

Virgil Percec