Dow Agrosciences LLC

Sangamo Biosciences, Inc.

Sangamo Therapeutics, Inc.

Corteva Agriscience LLC

Vipula Shukla

Fyodor Urnov

Ignacio Mario Larrinua

Sarah E Worden

Holly Jean Butler

Jeffrey C Miller

Manju Gupta

Joseph F Petolino

Lakshmi Sastry-Dent

Dmitry Y Guschin

Nicole Arnold

Paul Bundock

Avutu Sambi Reddy

Ryan C Blue

Jon Christopher Mitchell

Qihua C Cai

Robbi J Garrison

James Patrick Connell

Michiel Jan De Both

Lisa W Baker

Aaron Todd Woosley

Pamela Rene Haygood

Zihua Hu

David Richard Corbin

Yannick Doyon

Kelley Ann Smith

Daniel Gachotte

Mark Allen Thompson

Randy J Pell

Yuejin Sun

Cristie Min Dewes

Barbara A Miller

Zhifang Gao

Beth Blakeslee

David A McCrery

J Vincent B Oriedo

Rodney Crosley

Anthony Thinh Ngoc Trieu

Anthony Trieu

Thaddeus Weglarz

Kelley L Ralph

Theodore Jack Letherer

Christie Min Dewes

Disclosed herein are methods and compositions for targeted modification of one or more endogenous plant malate dehydrogenase genes.

Targeted modification of malate dehydrogenase

Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described.

Optimized non-canonical zinc finger proteins

This invention relates to newly identified polynucleotides and polypeptides in the phytic acid biosynthetic pathways, variants and derivatives of the same; methods for making the polynucleotides, polypeptides, variants, derivatives and antagonists. In particular, the invention relates to polynucleotides encoding inositol polyphosphate 2-kinase (IPP2-K) and polypeptides exhibiting such activity to modulate the phytic acid biosynthesis in such a way as to decrease phytic acid and/or increase the non-phytic acid phosphorous, especially in corn or soy animal feedstuffs.

Inositol polyphosphate 2-kinase genes and uses thereof

Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into a plant Zp15 locus, for example, for expression of a polypeptide of interest.

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This invention encompasses the identification and isolation of genes that confer disease control properties in plants, as well as plants comprising such genes. These genes are derived from the following sources:(var.IR7),and(Rifai 1295-22). The control conferred is against the one or more of the following phytopathogens:-, and. Further, this invention encompasses other homologous and heterologous sequences with a high degree of functional similarity.

Nucleic acid compositions conferring disease resistance

The present invention relates to nucleic acid and amino acid sequences that confer herbicide resistance in plants, as well as herbicide resistance in plants, plant seeds, plant tissues and plant cells comprising such sequences. In a preferred embodiment, the sequences of the present invention confer a tolerant phenotype in plants in response to a chronic and/or acute inhibitin dose of auxinic herbicides. The present invention also provides homologous sequences with a high degree of functional similarity.

Nucleic acid compositions conferring herbicide resistance

This invention encompasses the identification and isolation genes and gene fragments that confer altered metabolic characteristics inplants, when expressed using GENEWARE&#x2122; viral vectors. These genes are derived from a variety of sources. Expression of these genes resulted in alterations of the levels of at least one of the following metabolites: acids, fatty acids, amino acids and related compounds, branched fatty acids, carbohydrates, hydrocarbons, alkaloids and other bases, esters, glycerides, phenols and related compounds, alcohols, alkenes and alkynes, sterols, oxygenated terpenes, and other isoprenoids, and ketones and quinones.

Nucleic acid compositions conferring altered metabolic characteristics

This invention encompasses the identification and isolation of genes that confer disease control properties in plants, as well as plants comprising such genes. These genes are derived from the following sources:(var. Indica IR7), Papaver rhoeas,and(Rifai 1295-22). The control conferred is against the one or more of the following phytopathogens:, Cercospora zeae-maydis,, and. Further, this invention encompasses other homologous and heterologous sequences with a high degree of functional similarity.

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Indianapolis, IN, United States of America

Vipula Shukla