Ucb Pharma, S.a.

Ucb S.a.

Ucb Farchim Sa

Violeta Marmon

Emile Cavoy

Celal Ates

John Surtees

Edmond Differding

Anne-Catherine Burteau

Vincent Zimmermann

The present invention relates to an improved process for the preparation of (S)-(&#x2212;)-&#x3b1;-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein Ris methyl or ethyl; and Ris C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes. 

Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues

The present invention relates to an improved process for the preparation of (S)-(&#x2212;)-&#x3b1;-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein Ris methyl or ethyl; and Ris C?2#191&#x2013;C?4#191 alkyl, C?2#191&#x2013;C?4#191 alkenyl or C?2#191&#x2013;C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes 

Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues

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Abingdon-Oxon, United Kingdom

Violeta Marmon