Sun Pharmaceutical Industries Limited

Vinod Sampatrao Burade

Rajamannar Thennati

Nishith C Chaturvedi

Muthukumaran Natarajan

Dhiren Rameshchandra Joshi

Brijeshkumar Patel

Ravishankara Madavati Nagaraja

Pradeep Dinesh Shahi

Krunal Harishbhai Soni

Rishit Mansukhlal Zalawadia

Abhishek Tiwari

Vipulkumar Shankarbhai Patel

Kunal Pandya

The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.

GLP-1 analogues

Growing community of inventors

Gujarat, India

Vinod Sampatrao Burade