Council of Scientific and Industrial Research

Vinod Kumar Khanna

Mannepalli Lakshmi Kantam

Sunkara Sakunthala Madhavendra

Sunkam Vanaja

Mandapati Jayalakshmi

Shamim Ahmad

Yogendra Kumar Jain

Mandapati Mohan Rao

Sunkara Vardhireddy Manorama

Isukapally Margaret

Chandra Sekhar

Kaki Rajgopal

Chandra Shekhar

Mannepalli Lekshmi Kantam

Sunkara Vardhirreddy Manorama

Shamim Ahmed

The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Selective Field Effect Transister) coated with molecular imprint of cholesterol on the SiO+SiNdielectric gate of the said electrode. The molecular imprint of cholesterol (MIPC) anchored in to a silica matrix sensing material is identified as a sensing material which has specific selectivity towards the cholesterol in presence of other organic constituents in human blood serum.

Potentiometric cholesterol sensor for the quantitative estimation of total cholesterol in human blood serum

The present invention relates to the development of a biosensor to determine potassium in human blood serum using dibenzo-18-crown-6 (DB18C6) as ionophore. Human blood serum contains potassium in ppm levels i.e 137 to 200 mg/litre and sodium co exists with a 30 times higher concentration. Such a high concentration tends to interfere the selectivity towards potassium, but DB18C6 proves to have an excellent selectivity towards potassium and is highly sensitive to the lowest concentration of potassium levels present in the human blood serum. So the present invention reports the fabrication and characterization of ISFET (Ion Selective Field Effect transistor) coated with a monolayer of crown ether, dissolved in chloroform, on the gate of electrode.

Biosensor to determine potassium concentration in human blood serum

Growing community of inventors

Pilani, India

Vinod Kumar Khanna