Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a.

Vincenzo Russo

Elisa Liberati

Nicola Cazzolla

Guido Furlotti

Giorgina Mangano

Maria Alessandra Alisi

Lorenzo Polenzani

Patrizia Dragone

Isabella Coletta

Leonardo Marchitto

Lorella Ragni

Giuseppe Biondi

Giovanni Battista Ciottoli

Serena Tongiani

Stefano Selva

Giuseppe (deceased) Biondi

The present invention relates to glycogen-based polymers and the use thereof for enhancing the solubility in water of lipophilic compounds, to complexes of the said glycogen-based polymers with lipophilic compounds and the use thereof for administering lipophilic compounds, and to pharmaceutical, nutraceutical, and cosmetic compositions comprising the said complexes.

Glycogen-based water solubility enhancers

The present invention relates to glycogen-based cationic polymers, to complexes of the said cationic polymers with anionic compounds, to pharmaceutical compositions comprising the said complexes, and to the use of the said complexes for delivering or transfecting the said anionic compounds to a specific pharmacological target, such as, for instance an organ, a tissue or a cell.

Glycogen-based cationic polymers

The present invention relates to a controlled release pharmaceutical or food formulation comprising at least one active pharmaceutical or food ingredient dispersed in a mixture of a glycogen with a polysaccharide, and the process for its preparation. The invention also relates to a slow release system represented by a mixture of a glycogen with a polysaccharide, and its use for the preparation of slow release pharmaceutical or food formulations.

Controlled release pharmaceutical or food formulation and process for its preparation

The present invention relates to a food formulation for the controlled release of glucose comprising glycogen and at least one other edible component, as well the use of glycogen for its preparation.

Food formulation comprising glycogen

Slow-release excipients which comprise an association of at least one glycogen and at least one alginate with an alkaline-earth metal salt are useful for the preparation of slow-release pharmaceutical formulations.

Slow-release pharmaceutical formulation and process for its preparation

A method for treating an inflammatory process selected from the group consisting of oedema, erythema, articular inflammation, rheumatoid arthritis, arthrosis, a colorectal tumor, a pulmonary carcinoma, an adenocarcinoma, and combinations thereof, in a person in need thereof, the method comprising administering to the person in need thereof, in an amount sufficient to treat the inflammatory process, a 3-aminocarbazole or a salt thereof.

3-aminocarbazole compounds, pharmaceutical composition containing the same and method for the preparation thereof

A compound of formula (I), in which R1, R2, R3, R4, R5, R6, X and Y have the meanings indicated in the description, and the pharmaceutically acceptable salts thereof. A pharmaceutical composition containing a compound of formula (I) or a pharmaceutically acceptable salt thereof. A method for preparing the abovementioned compound of formula (I) and the pharmaceutically acceptable salts thereof. 

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Rome, Italy

Vincenzo Russo