Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Avalun

Sanofi Pasteur Inc.

Vincent Poher

Patrick Pouteau

Cedric Allier

Myriam-Laure Cubizolles

Cédric Allier

Johanna Spiaczka

Jean Berthier

Philippe Peltie

Maxime Huet

Frederic Ronzon

Frederic Fantoni

Paul Laurens

Frédéric Ronzon

Christian Valentin

Gwenola Sabatte

Véronique Mourier

Frédéric Fantoni

A device for collecting a liquid sample by capillarity includes distinct first and second elements having respective male and female parts. The male part comprises a channel having a transverse section. The female part comprises a peripheral wall that transversely delimits a cavity to house the male part. A part of the peripheral wall forms a cap to close the transverse section when the female part houses the male part.

Device for collecting a liquid sample by capillarity

A device for taking a sample of liquid by capillarity, including a channel for flow of the liquid delimited by two internal walls of the device between which a channel bottom extends, the distance separating the two internal walls decreasing in the direction of the channel bottom, the channel extending between a first collecting end, open onto outside of the device and configured to receive the liquid, and a second end, to enable the liquid to flow by capillarity along the channel bottom from the first end towards the second end. The channel includes, at the second end, a blocking structure to block the flow of liquid in the channel from the first end towards the second end.

Device for taking a liquid sample by capillarity and associated analysis method

The invention relates to a system for analyzing a liquid sample, including an analysis device comprising a casing including a through-opening leading into a housing adapted to receive a portion of a collecting device and extending longitudinally from the opening along an axis of insertion of the collecting device. The analysis system further includes a collecting device comprising a main body extending along a longitudinal axis and including a fluid chamber adapted to be inserted in the housing along the insertion axis and a receiving surface intended to receive the liquid sample extending substantially orthogonally relative to the axis of the main body.

System for analyzing a liquid sample

The method is provided for characterizing agglomeration of particles in a liquid containing an analyte, including introducing liquid into a fluid chamber; mixing the liquid with a bifunctional reagent, lighting the fluid chamber using an excitation light beam extending through the fluid chamber in a longitudinal direction (X); acquiring at least one image using a matrix photodetector, each image including pixels (I(x,y), x,y representing the coordinates of a pixel of an image, the image (I(x,y)) being formed by radiation transmitted by the lighted fluid chamber; and calculating from at least one acquired image (I(x,y)), at least one indicator (Ind) characterizing the particle agglomeration. The photodetector can be positioned less than 1 cm from the fluid chamber, and during the calculation step, the calculated indicator (Ind) is representative of the intensity of the pixels of the image. The method advantageously allows for characterizing the agglomeration of particles in a liquid.

Method and system for characterizing the agglomeration or speed of particles contained in a liquid, such as blood particles

This method for estimating the quantity of an analyte contained in a liquid includes the following steps:

Method and system for estimating the quantity of an analyte contained in a liquid

The method according to the invention is capable of characterizing a variation in the speed of particles or agglomeration of particles, the particles, such as blood particles, being contained in a liquid (). The characterization method includes the following steps: During the acquisition step, the photodetector () is positioned at a distance (D) smaller than 1 cm from the fluid chamber () in the longitudinal direction (X).

Method and system for characterizing the movement speed of particles contained in a liquid, such as blood particles

The invention relates to a method for estimating the amount of entities deposited on microparticles in suspension in a solution, and also to an associated device. The method comprises the following steps:

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Guines, France

Vincent Poher