Centre National De La Recherche Scientifique

National Institute of Health and Medical Research

Université Nice Sophia Antipolis

Vincent Malnuit

Rachid Benhida

Guillaume Robert

Patrick Auberger

Alexandre Puissant

Mohsine Driowya

Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described.

Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same

Growing community of inventors

Nice, France

Vincent Malnuit