Dow Global Technolgoies LLC

Rohm & Haas Electronic Materials LLC

Exogenesis Corporation

Exogenesis Biomedical Technology

Vincent DiFilippo

Stephen M Blinn

Barry M Zide

Jitendra Singh Goela

Sean R Kirkpatrick

Michael A Pickering

Hangyao Wang

Hua Bai

Debashis Chakraborty

Heather A G Stern

An apparatus includes a manifold with a chamber for mixing multiple reactants. Gases are jetted into the manifold by a plurality of inlet injectors. The inlet injectors are arranged such that the gases passing into the manifold impinge on each other at a common point to form a mixture. The mixture passes through a plurality of holes in one side of the manifold into a deposition chamber where the mixture of gases impinges on additional gases at a common point to provide a reaction resulting in deposition of solid materials in the deposition chamber. The solid materials are free-standing.

Apparatus and method for producing free-standing materials

Methods of implanting, applying, or adhering various drug molecules directly into or onto the surface of medical devices through gas cluster ion beam (GCIB) and/or monomer ion beam surface modification of the medical devices before or after depositing the various drug molecules onto the medical devices.

Methods of adhering drugs to the surface of medical devices through ion beam surface modification

Regardless of the materials used in an artificial joint component design, the present invention applies gas cluster ion beam (GCIB) technology in order to modify the component's surface(s) so as to increase lubrication between contact surfaces, thereby substantially reducing wear debris, osteolysis complications, and accelerated wear failure. The approach of the surface modification comprises an atomic level surface patterning utilizing GCIB to apply a predetermined pattern to the surface(s) of the joint implant to reduce frictional wear at the interface of the surfaces. A reduction in wear debris by GCIB patterning on any surface(s) of a joint prosthesis reduces accelerated failure due to wear and osteolysis and results in a substantial cost savings to the healthcare system, and reduces patient pain and suffering.

Method and system for improving the effectiveness of artificial joints by the application of gas cluster ion beam technology

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North Chelmsford, MA, United States of America

Vincent DiFilippo