Schering Corporation

Vilas A Dahanukar

Ilia A Zavialov

Hoa N Nguyen

Fucheng Zhang

Cecilia A Orr

A process for preparing xanthine phosphodiesterase V inhibitors, and compounds utilized in said process. The process includes a five-step methodology for efficient synthesis of Compound 5 without intermediate purifications or separations, a dihalogenation step to synthesize Compound 7, and a coupling reaction to produce Compound 9.   

Process for preparing xanthine phosphodiesterase V inhibitors and precursors thereof

A process for preparing xanthine phosphodiesterase V inhibitors, and compounds utilized in said process. The process includes a five-step methodology for efficient synthesis of Compound 5 without intermediate purifications or separations, a dihalogenation step to synthesize Compound 7, and a coupling reaction to produce Compound 9 

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Edison, NJ, United States of America

Vilas A Dahanukar