University of Illinois

Viktor Malyarchuk

John A Rogers

Ralph G Nuzzo

Nathan H Mack

Li Gao

Richard Chad Webb

Matthew Stewart

Jimin Yao

Provided are tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin. The devices conformally mount to the tissue and have one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors to detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and/or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters.

Epidermal devices for analysis of temperature and thermal transport characteristics

The present invention provides plasmonic crystals comprising three-dimensional and quasi comprising three-dimensional distributions of metallic or semiconducting films, including multi-layered crystal structures comprising nanostructured films and film arrays. Plasmonic crystals of the present invention include precisely registered and deterministically selected nonplanar crystal geometries and spatial distributions providing highly coupled, localized plasmonic responses in thin film elements and/or nanostructures of the crystal. Coupling of plasmonic responses provided by three-dimensional and quasi-three dimensional plasmonic crystal geometries and structures of the present invention generates enhanced local plasmonic field distributions useful for detecting small changes in the composition of an external dielectric environment proximate to a sensing surface of the plasmonic crystal. Plasmonic crystal structures of the present invention are also useful for providing highly localized excitation and/or imaging of fluorophores proximate to the crystal surface.

Multispectral plasmonic crystal sensors

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Urbana, IL, United States of America

Viktor Malyarchuk