International Minerals & Chemical Corp.

Pitman-moore, Inc.

Mallinckrodt Veterinary, Inc.

Vikram P Mehrotra

Brian R Schricker

Ray E Barker

Paul C Chieng

Kallidaikurichi N Sivaramakrishnan

James R McMullen

Chin-Liang Chou

Donald R Hahn

A method for producing lysocellin in bead form comprises: (a) cultivating a lysocellin-producing microorganism in an aqueous nutrient-containing fermentation broth under lysocellin-producing conditions; (b) adding a base or inorganic phosphate to the fermentation broth within about the first 24 hours of the beginning of the fermentation in an amount sufficient to ensure that the lysocellin is produced in the form of a cation salt of lysocellin; (c) providing a lipid to the fermentation broth such that the lipid is present in the broth in a sufficient amount to form discrete beads with the lysocellin in the fermentation broth; and (d) separating the beads from the broth.

Preparation of lysocellin beads by fermentation

A method for recovering a recombinant protein from a protein solution containing high molecular weight containing proteins by directly adding amine or quaternary ammonium compounds to the solution in amounts sufficient to selectively precipitate the high molecular weight protein contaminants. The high molecular weight precipitates are removed and the solution is further processed to remove low molecular weight contaminating proteins and other non-protein contaminants. The recombinant protein is subsequently recovered and further processed to produce a protein composition suitable for its intended use.

Method for recovering recombinant proteins

A method for recovering a recombinant protein from a protein solution containing high molecular weight contaminating proteins by directly adding a flocculant to the solution in amounts sufficient to selectively precipitate the high molecular weight protein contaminants is disclosed. The high molecular weight precipitates are removed and the solution is further processed to remove low molecular weight contaminating proteins and other non-protein contaminants. The recombinant protein is subsequently recovered and further processed to produce a protein composition suitable for its intended use.

An aqueous medium having dispersed therein hydrophobic, polyether antibiotic-containing droplets, is mixed to cause the droplets to collide with each other and coalesce to form agglomerates which are separable from the medium.

Recovery of polyether antibiotic material

A method of producing pure and dense amorphous fused synthetic silica. Silica of desired purity is wet pelletized or agglomerated to form particles having an average particle size of between about 5 and 2500 microns. These particles are calcined to volatilize impurities and increase density to at least about 0.9 g/cm.sup.3. Calcined particles are classified by size or reduced in size if desired or needed by grinding in such a way that the purity of the product is maintained.

Process for producing pure and dense amorphous synthetic silica particles

A method of producing a high purity silica powder which can be fused to form transparent, bubble-free particles. An ammonium fluosilicate solution is purified preliminarily by removing colloidal-sized silica onto which impurities in the solution have been adsorbed. The high purity powder is produced by ammoniation of an unsaturated aqueous solution of ammonium fluosilicate. Silica powder produced is filtered, washed, and dried before fusion. Additional pre-fusion treatments such as washing, hydrothermal leaching, calcination, and a combination thereof, may be utilized to ensure that the concentration of volatile material is low.

Method of production of high purity fusible silica

High purity fused silica particles are made by heating relatively low density silica flour in a high temperature flame. The silica flour feed rate, flame temperature, and collection zone temperature are adjusted to produce an aggregate of surface-bonded fused silica particles. The aggregate is shaped like a honeycomb and can be ground autogenously without introducing impurities into the final product.

Process for producing high purity fused quartz powder

A pelletized feed supplement is supplied which effectively increases productivity of animals fed high acid producing diets. The pelletized feed supplement can also be used to neutralize stomach acid of humans and to maintain a proper electrolyte balance. A method is taught of producing the pelletized feed supplement which results in a buffering agent which is dissolved gradually, and has a high buffering capacity.

Ruminant feed antacid containing potassium, sodium and chlorine

A new froth flotation collecting agent and an improved flotation process for beneficiating silica-containing ores, particularly phosphate ores, are provided. In the process, silica particles are selectively separated, by froth flotation, as a froth phase from mineral particles, particularly phosphate particles, remaining in an aqueous concentrate phase in the presence of a silica-activating ion and a mixed collecting agent containing an anionic collector and a cationic collector.

Collecting agents for use in the froth flotation of silica-containing

The amount of carbonate mineral impurities is reduced in aqueous phosphate rock slurry by (a) conditioning the slurry with an effective amount of CO.sub.2, (b) adding an effective amount of an anionic collector to the slurry and (c) subjecting the slurry to a froth flotation process whereby the carbonate mineral impurities are concentrated in the froth. The CO.sub.2 acts to depress flotation of phosphate minerals relative to the carbonate mineral impurities.

Growing community of inventors

Terre Haute, IN, United States of America

Vikram P Mehrotra