Allergan, Inc.

Almirall, LLC

Hovione Scientia Limited

Hovione International Limited

Adare Pharmaceuticals, Inc.

Vijaya Swaminathan

Varsha D Bhatt

Kevin S Warner

Ajay P Parashar

Arturo Angel

Mohammad Salman

Gopi M Venkatesh

Jin-Wang Lai

James M Clevenger

George Magrath

Varsha Bhatt

Dapsone and dapsone/adapalene compositions can be useful for treating a variety of dermatological conditions. The compositions of this disclosure include dapsone and/or adapalene in a polymeric viscosity builder. Subject compositions can be adjusted to optimize the dermal delivery profile of dapsone to effectively treat dermatological conditions and improve the efficiency of pharmaceutical products applied to the skin. Use of the polymeric viscosity builder provides compositions with increased concentrations of diethylene glycol monoethyl ether relative to compositions without the polymeric viscosity builder.

Topical dapsone and dapsone/adapalene compositions and methods for use thereof

Topical dapsone and dapsone/adaplene compositions and methods for use thereof

The invention relates to a topical suspension formulation that includes a tetracycline, a liquid medium and a polymeric gelling agent. The tetracycline may be in the form of its pharmaceutically acceptable salts, hydrates, or polymorphs and is in a suspended form within the formulation. The liquid medium is selected such that it does not dissolve or substantially minimally dissolves the tetracycline. The gelling agent is a polymeric hydrocarbon gelling agent. Preferably, the tetracycline has a particle size of less than or equal to about 20 microns.

Tetracycline topical formulations, preparation and uses thereof in treating an ocular condition

Tetracycline topical formulations, preparation and uses thereof

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San Francisco, CA, United States of America

Vijaya Swaminathan