University of Alberta

The Secretary of State for Environment, Food and Rural Affairs

Vijaya Ganesh Narayanaswamy

David R Bundle

John McGiven

Laurence Howells

Julie Guiard

David Bundle

John Mcgiven

There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-&#x3b1;-pyranose and comprising at least one -(1-3)- link between adjacent 4,6-dideoxy-4-acylamido-&#x3b1;-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from &#x2014;CHOH, &#x2014;H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.

Oligosaccharide conjugates and methods of use

There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-&#x3b1;-pyranose and comprising at least one -(1-3)-link between adjacent 4,6-dideoxy-4-acylamido-&#x3b1;-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from &#x2014;CHOH, &#x2014;H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.

Growing community of inventors

Toronto, Canada

Vijaya Ganesh Narayanaswamy