Suven Life Sciences Limited

Vijay Sidram Benade

Venkateswarlu Jasti

Ramakrishna Nirogi

Anil Karbhari Shinde

Abdul Rasheed Mohammed

Pradeep Jayarajan

Ramkumar Subramanian

Gopinadh Bhyrapuneni

Vinod Kumar Goyal

Santosh Kumar Pandey

Jyothsna Ravula

Rajesh Kumar Badange

Renny Abraham

Saivishal Daripelli

Kumar Bojja

Narsimha Bogaraju

Veena Reballi

Venkata Ramalingayya Grandhi

Venkatesh Goura

Satish Jetta

Raghava Chowdary Palacharla

The present invention relates to heteroalicyclic compounds represented by the general formula (I), or their isotopic forms, stereoisomers, or pharmaceutically acceptable salts thereof. The present invention also describes a method of making such compounds, pharmaceutical compositions comprising such compounds and their use for the treatment or prevention of central nervous system related disorders.

Substituted piperidines and piperazines and methods for the treatment of CNS disorders

The present invention relates to substituted heterocyclic compounds represented by the general formula (I), or their isotopic forms, stereoisomers, or pharmaceutically acceptable salts thereof. The present invention also describes the method of making such compounds, pharmaceutical compositions comprising such compounds and their use in the treatment of central nervous system disorders.

Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders

The present invention relates to new uses of a 5-HTreceptor agonist, specifically Isopropyl-3-{5-[1-(3-methoxypropyl)piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}-1H-indazole (Compound-1) or a pharmaceutically acceptable salts thereof, for the treatment of dementia due to menopause, senile dementia, cognitive deficits associated with schizophrenia, depression, chemotherapy-induced cognitive impairment, and behavioral and psychological symptoms of dementia such as apathy/indifference, agitation, aggression, depression, anxiety, irritability/lability, dysphoria, aberrant motor behavior, delusions, hallucinations, elation/euphoria, psychosis, disinhibition, sleep and night time behavior disorders or appetite and eating disorders. The present invention further provides use of the 5-HT4 receptor agonist in the manufacture of medicament intended for the treatment of the disorders described herein.

Uses of a 5-HT4 receptor agonist

The present invention relates to pyrrolo[1,2-b]-2-pyridazinone compounds of formula (I), or their isotopic forms, stereoisomers, or pharmaceutically acceptable salts thereof as 5-HTreceptor agonists. The present invention also describes methods of making such compounds, pharmaceutical compositions comprising such compounds, and their use in the treatment of gastrointestinal disease or disorder.

Pyrrolo[1,2-b]-2-pyridazinone compounds as 5-HT4 receptor agonists

The present invention provides new methods of treatment for narcolepsy, excessive daytime sleepiness, obstructive sleep apnea, circadian rhythm sleep disorders, sleep and vigilance disorders associated with Parkinson's disease, multiple sclerosis, dementia or attention deficit hyperactivity disorder by administering a therapeutically effect amount of histamine-3 receptor (H3R) inverse agonist, N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide or a pharmaceutically acceptable salt thereof. The present invention further provides use of the said compounds in the manufacture of medicament intended for the treatment of the disorders described herein.

Method of treatment with histamine-3 receptor inverse agonist

The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor. (Formula I)(I) 

Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators

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Telangana, India

Vijay Sidram Benade