Koninklijke Philips Corporation N.v.

Ric Investments, Inc.

Vijay Kumar Iyer

Michael Edward Colbaugh

Erik Kurt Witt

Douglas M Mechlenburg

Uday S Shankar

Edmund Arnliot Shaw

George Zonios

Ronald Dean Dean Fligge

Nathan Zimmerman

An apparatus for use in diagnosing the presence of obstructive sleep apnea (OSA) in a patient includes a sensing module structured to measure a parameter indicative of a tremor in the patient's neck, tongue and/or throat muscles while the patient is awake, the parameter not being airflow through the patient's airway. The sensing module generates one or more electrical signals based on the measured parameter. The apparatus also includes a processor operatively coupled to the sensing module, the processor being structured to receive the one or more electrical signals, perform an analysis of the one or more electrical signals, and based on the analysis determine whether the tremor has a frequency in at least one predetermined frequency range that is indicative of OSA.

Method and apparatus for diagnosing obstructive sleep apnea with an awake patient

A respiration appliance () is configured to entrain the breathing of the subject. The breathing of the subject is entrained to modulate the autonomic nervous system of the subject to decrease sympathetic nerve activity and/or to reduce sympathetic/parasympathetic balance in order to provide relaxation to the subject. The respiration appliance () restricts the exhalation of the subject, while permitting substantially unencumbered inhalation, to impact the breathing of the subject in a manner that enhances relaxation.

System and method for entraining the breathing of a subject

A method of treating obstructive sleep apnea comprising reducing an effective amount of extracellular fluid of a patient suffering from obstructive sleep apnea.

Pre-emptive fluid shifts to treat obstructive sleep apnea

A method for calibrating a pulse oximeter device and an apparatus incorporating the method and a system for utilizing the method. The method is based on modeling light propagation in tissue at two wavelengths, typically, one in the red and one in the infrared range of the spectrum. A formula is derived relating the arterial oxygen saturation to a ratio R commonly measured by standard pulse oximeters. A specific parameter is identified and utilized in the calibration of the oximeter. This parameter is formulated in terms of the DC signals measured by the pulse oximeter at the two wavelengths. An empirical method for estimating this parameter based on experimental data is also described.

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Export, PA, United States of America

Vijay Kumar Iyer