Cook Medical Technologies LLC

Wilson-cook Medical Incorporated

The General Hospital Corporation

University of Pennsylvania

Muffin Incorporated

Wilmington Trust, National Association, As Collateral Agent

Baystate Health, Inc.

The General Hospital Corporation D/b/a Massachusetts General Hospital

Vihar C Surti

Tyler Evans McLawhorn

John Crowder Sigmon, Jr

Michelle D Martinez

Shaun D Gittard

Richard W Ducharme

Kenneth F Binmoeller

Gregory James Hardy

Kiyoshi Hashiba

Kenneth C Kennedy, Ii

William S Gibbons, Jr

Tyler E Mclawhorn

David F Waller

Travis E Dillon

Kimberly K Ingram

Matthew P Carter

David M Hardin, Jr

Andres F Aguirre

David Keith Piech

Jillian Haac

David R Wagner

Annette Fritscher-Ravens

Deepthi Jampala

David M Hardin

Kenneth C Kennedy

Neal E Fearnot

Jeffry Scott Melsheimer

William John Havel

Charles W Agnew

Richard B Sisken

Eugene Skelton

Brian K Rucker

Jeremy T Newkirk

Stephen E Deal

Hilbert Brown

Danny Azriel Sherwinter

Frederick B Haller

Martin Bruggeman

Christopher A Carruthers

Michael Brecht

Wenfeng Lu

Liam Breen

David Desilets

John C Sigmon

Jillian Faye Hrnicek

Gregory Hardy

Andrea C Mydosh

Laura Johnson

Smitha Smith

Patricia J Chilton

Zahid Saeed

Michelle Martinez

Devesh Amatya

Travis Benton Johnson

Marcie G Yount

Field F Willingham

Michael L Kochman

Ashwin Rajan Sakhare

Eric Young

Antoine Clark

Mario Zaritzky

Roy M Soetikno

Leonard Erickson

Eugene E Skelton

Martin J Bruggeman

Andres F Aquirre

M D Binmoeller

Hilbert D Brown

The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Medical scopes for delivering therapeutic agents

The present invention relates to a long-lasting medical product for protecting or treating a lesion in the gastrointestinal tract. The medical product includes a protective covering, wherein the medical product upon application at and about the site of the lesion adheres to the gastrointestinal tissue and is capable of remaining at and about the site of the lesion for a time sufficient to allow the lesion to heal or be treated.

Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding

Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Medical devices with detachable pivotable jaws

A scope system is provided including an elongate tube with a distal portion and a lumen extending therethrough. The scope system also includes at least one accessory channel including a tubular structure with an accessory lumen extending therethrough, the at least one accessory channel movably disposed at least partially within the lumen of the elongate tube. The at least one accessory channel includes a distal section and a forward-viewing configuration and a side-viewing configuration. In the forward-viewing configuration, the distal section of the at least one accessory channel is substantially parallel to the distal portion of the elongate tube and in the side-viewing configuration, the distal section of the at least one accessory channel is arced at a radius greater than a radius of the distal portion of the elongate tube.

Flexible endoscopic support system

An expandable dilation member may include a proximally-tapered portion to dilate a stricture. The dilation member may be distally advanced in an unexpanded state over a wire guide through the stricture. The dilation member may then be configured in an expanded state, where the dilation member has a longitudinal profile that includes the proximally-tapered portion. A handle assembly proximally pulls the dilation member in the expanded state. In response, the proximally-tapered portion engages with and biases the stricture. When biasing the stricture, the proximally-tapered portion exerts a plurality of different types of forces, including a shearing force, a radial force, and in some procedures, a torsional force. In some embodiments, the proximally-tapered portion has a continuous taper from a smallest diameter to a largest diameter. In other embodiments, the proximally-tapered portion has at least one constant-diameter portion longitudinally disposed in between the smallest diameter and the largest diameter.

Dilation procedures with expandable dilation devices

Methods of modifying the luminal profile of a body vessel are described. An example method comprises advancing a cannula out of the distal end of a catheter disposed within the lumen of a body vessel of an animal and toward a target site on the wall of the body vessel; passing contrast dye through the cannula toward the target site; simultaneously continuing the advancing and passing until the distal end of the cannula punctures the inner layer of the wall of the body vessel at the target site; and passing a bulking agent through the cannula and into a space between connective tissue layers surrounding the vessel wall at the target site. Medical devices, medical device assemblies, and kits are also described.

Methods, medical devices and kits for modifying the luminal profile of a body vessel

A scope system is provided including an elongate tube with a distal portion and a lumen extending therethrough. The scope system also includes at least one accessory channel extending from a proximal end to a distal end and having with an accessory lumen extending therethrough, the at least one accessory channel movably disposed at least partially within the lumen of the elongate tube. The at least one accessory channel includes a distal section and a forward-viewing configuration and a side-viewing configuration. In the forward-viewing configuration, the distal section of the at least one accessory channel is substantially parallel to the distal portion of the elongate tube and in the side-viewing configuration, the distal section of the at least one accessory channel is arced at a radius greater than a radius of the distal portion of the elongate tube.

Deflecting endoscope accessory channels

Among other things, there are shown embodiments of locking mechanisms for holding sutures in tension. Such devices may be used with implants that use or require sutures, and are easily locked remotely. In particular embodiments, a lock includes a housing member, a pin member at least partially within the housing member, and a spring biasing the pin member into the housing member. The pin member includes a gripping portion, and has a retracted condition and a locked condition. When retracted, a suture can move through the housing member and around the gripping portion of the pin member. When locked, the gripping portion of the pin member engages the suture and presses it against the interior of the housing member.

Suture lock device

The present embodiments provide apparatus and methods for treating tissue by applying a force to the tissue. In one embodiment, the apparatus comprises a deployable segment having proximal and distal regions, a main body extending therebetween, and a loop member formed at the distal region of the deployable segment. A cannula having a bore is dimensioned to circumferentially surround at least a portion of the main body at a location proximal to the loop member, and a spring member is disposed between the cannula and the loop member. The proximal end of the spring member is affixed to the cannula, and the distal end of the spring member is movable to apply a compressive force to adjust the size of the opening of the loop member and compress tissue disposed within the opening of the loop member. In an alternative embodiment, the cannula is omitted, and a diameter of the loop member is configured to be reduced and increased any number of times before final deployment of the deployable segment.

Apparatus and methods for maintaining a force upon tissue using a loop member

Growing community of inventors

Winston-Salem, NC, United States of America

Vihar C Surti