Smithkline Beecham Corporation

Hoffmann-la Roche Inc.

Glaxo Group Limited

Victor Witold Jacewicz

Neal Ward

Keith Biggadike

Steven John Coote

Andrew Simon Craig

Michael John Millan

John Frederick Seager

Andrew L Theophilus

Rosalyn Kay Nice

Brian Noga

David Malcolm Crowe

Richard Keith Anderson

Andrew Lewis Theophilus

Olga Chetina

David Alan Jones

Michael Anthony Harris

There is provided a crystalline complex comprising a compound of formula (I) in which the crystal lattice is stabilized by the presence of a guest molecule, characterized in that the crystalline complex is of space group P222having unit cell dimensions of about 12.5&#xb1;1.0 &#xa7;, 15&#xb1;1.0 &#xa7;, and 16.2&#xb1;1.0 &#xa7; when determined at either 120K or 150K.

Crystalline complexes of fluticasone-2-furoate

There is provided a crystalline chemical composition comprising a compound of formula (I)in which the crystal lattice is stabilized by the presence of a guest molecule, characterized in the crystalline composition is of space group P222having unit cell dimensions of about 7.6&#xb1;0.6 &#x212b;, 12.7&#xb1;0.7 &#x212b;, and 33&#xb1;3 &#x212b; when determined at 120 K.

Anti-inflammatory androstane derivative compositions

A process for preparing granisetron by cyclising a compound of structure (2).

Process for the preparation of granisetron

Invented are methods of treatment using novel forms of paroxetine hydrochloride anhydrate.

Paroxetine hydrochloride form A or C

Form of

'Paroxetine hydrochloride (I) anhydrate free of bound propan-2-ol, and various forms thereof, are useful in the treatment of depression and other disorders for which administration of selective serotonin reuptake inhibitors are indicated.'

Paroxetine hydrochloride form A

'Paroxetine hydrochloride (I) anhydrate ##STR1## free of bound propan-2-ol, and various forms thereof, are useful in the treatment of depression and other disorders for which administration of selective serotonin reuptake inhibitors are indicated.'

Form of paroxetine hydrochloride anhydrate

The present invention relates to paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol, several forms of the above, processes for preparing the above, new intermediates useful in preparing the above and methods of treating and/or preventing certain diseases by administering the compounds of the invention to a patient in need thereof.

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Tunbridge Wells, United Kingdom

Victor Witold Jacewicz