Faes Farma, S.a.

Victor Rubio Royo

Melchor Alvarez De Mon Soto

Antonio De La Hera Martinez

Ana Munoz Munoz

Aurelio Orjales Venero

Maria Luisa Lucero De Pablo

Ramon Mosquera Pestaña

Maravillas Bordell Martin

Gonzalo Canal Mori

Haydee Blanco Fuente

Ramon Mosquera Pestana

A compound of formula (I): or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, and a method for the treatment of an acute or chronic inflammatory disease by inhibiting the production of at least one pro-inflammatory cytokine selected from TNF-alpha, IFN-gamma, IL-8 and IL-10, involving administering to a patient in need of such treatment a therapeutically effective amount of a compound of formula (I) as defined above.

5-(4-methanesulfonyl-phenyl)-thiazole derivatives for the treatment of acute and chronic inflammatory diseases

The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, and to a method for the treatment an acute or chronic inflammatory disease by inhibiting the production of at least one pro-inflammatory cytokine selected from TNF-alpha, IFN-gamma, IL-8 and IL-10, which comprises administering to a patient who needs such treatment a therapeutically effective amount of a compound of formula (I) as defined above.

Crystalline form 1 of 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1 -piperidinyl]ethyl]-&#x3b1;&#x3b1;-dimethyl-benzen&#x2296;eacetic acid Crystalline form 1 of 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1 -piperidinyl]ethyl]-&#x3b1;&#x3b1;-dimethyl-benzen&#x2296;eacetic acid of formula (I) is described, procedures for its preparation, pharmaceutical formulae containing crystalline form 1 and the use of crystalline form 1 to treat allergic reactions and pathological processes mediated by histamine in mammals such as man. 

Polymorph of 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1-piperidinyl]ethyl]-&#x3b1;&#x3b1;-dimethyl-benzeneacetic acid

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Leioa-Vizcaya, Spain

Victor Rubio Royo