Medtronic, Inc.

Cordis Corporation

Telectronics Pacing Systems, Inc.

Paceart Inc.

Victor Parsonnet

William J Combs

Tibor A Nappholz

Michael N Bergelson

Alan D Bernstein

Chih-Ming J Chiang

Tim Daily

The invention is directed to techniques for monitoring organ rejection. An implanted device monitors the impedance of the transplanted organ. When the impedance measurements indicate that the organ is being rejected, the device provides early warning of rejection.

Organ rejection monitoring

A diagnostic device for providing a prognosis of patient with an implanted cardiac device includes a data bank for storing statistical data relating various symptoms characterizing cardiac problems and associated complications. The device further includes an input device so that a clinician can enter patient specific data including his symptoms. A set of rules stored in a memory are used to provide a diagnosis for the patient based on the statistical data. Preferably the diagnostic device is incorporated in a programmer for a pacemaker or other implantable cardiac device.

Interactive probability based expert system for diagnosis of pacemaker

A method and apparatus for transmitting data descriptive of an electromagnetic waveform wherein a constant amplitude signal is frequency modulated and transmitted to a remote site where digital signals are generated in response to zero crossings of the fm analog signal. Interrupt signals are generated in response to zero crossings for storing time differences between successive digital signals corresponding to the zero crossing which are then averaged at the Nyquist sampling rate to display and analyze a constructed waveform simulating the original signal.

Method and apparatus for transmitting data descriptive of

The bipolar epicardial temporary pacing lead (10 or 110) comprises a lead body (22 or 122) containing first and second spaced apart wire conductors (24 or 124 and 26 or 126) each encased in insulating material (30 or 130) so as to form first and second insulated wire conductor portions (32 or 124 and 33 or 136). A straight needle (16 or 116) is connected to the proximal end portion (12 or 112) of the lead body (22 or 122). A curved needle (62 or 162) is connected to at least one of the wire conductors (24 or 124) at the distal end portion (14 or 114) of the lead (10 or 110). The distal end portion (14 or 114) of the lead (10 or 110) has insulation removed from portions of the respective first and second conductors (24 or 124 and 26 or 126) thereby to form in the distal end portion (14 or 114) a first or proximal electrode forming wire conductor portion (54 or 154) and a second or distal electrode forming or wire conductor portion (56 or 156). Terminal connector sleeves (34 and 36) are fixed on and around each insulated wire conductor portion (32 or 134 and 33 or 136) in the proximal end portion (12 or 112) of the lead (10 or 110) and in electrical contact with the wire conductor (24 or 124 and 26 or 126) therein.

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Millburn, NJ, United States of America

Victor Parsonnet