Biocircuits Corporation

Victor Pan

Hans Oliver Ribi

John Campbell Scott

Todd A Guion

Glenda L Choate

Joseph R Murdoch

Apparatus and methods are provided for the detection of analytes. A polyunsaturated polymerized lipid layer is employed, which is anisotropic, has a member of a specific binding pair bound to an end of the lipids, and whose optical characteristics are modified upon complex formation between the specific binding pair member and its complementary member. By providing for polarized light, linear and/or circular, one can detect the presence of complex formation by the change in the optical characteristics of the film. Polarizers, analyzers, and wave plates are employed for providing for a light signal which can be analyzed and related to the presence of an analyte in a sample.

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Burlingame, CA, United States of America

Victor Pan