Abbott Laboratories Corporation

Abbvie Inc.

Vicki L Nienaber

Jonathan Greer

Jeffrey Y Pan

Ronald B Jones

Jeffrey A Olson

Steven W Muchmore

Daniel W Norbeck

Milan Bruncko

Todd Warren Rockway

Vincent L Giranda

Daryl Richard Sauer

Jianchun Gong

Christopher R Dalton

Moshe Weitzberg

Celerino Abad-Zapatero

Willian J McClellan

William J Mcclellan

Method for mounting a sample comprising a crystal for X-ray crystallographic analysis, a method for aligning a sample comprising a crystal for X-ray crystallographic analysis, which sample is mounted on a positioning device, and a method for determining the structure of a sample containing a crystal by means of X-ray crystallography. The method includes activating a robot so that the tool retrieves the crystal holder, receives a sufficient amount of a fluid to maintain the crystal in the crystal holder at a temperature not in excess of about 160 degrees K, transfers the retrieved crystal holder to a positioning device, and mounts the transferred crystal holder on the positioning device, whereby the crystal in the retrieved crystal holder is maintained at a temperature not in excess of about 160 degrees K.

Automated sample handling for X-ray crystallography

Naphthamidine urokinase inhibitors

Method and apparatus for mounting a sample comprising a crystal for X-ray crystallographic analysis, a method for aligning a sample comprising a crystal for X-ray crystallographic analysis, which sample is mounted on a positioning device, and a method for determining the structure of a sample containing a crystal by means of X-ray crystallography.

Ligand screening and design by X-ray crystallography

Growing community of inventors

Gurnee, IL, United States of America

Vicki L Nienaber