Sigma-tau Industrie Farmaceutiche Riunite S.p.a.

Istituto Nazionale Per Lo Studio E La Cura Dei Tumori

Instituto Nazionale Per Lo Studio E La Cura Dei Tumori

Vesci Loredana

Maria Ornella Tinti

Mauro Marzi

Zunino Franco

Claudio Pisano

Domenico Alloatti

Cabri Walter

Alpegiani Marco

Vergani Domenico

Caludio Pisano

Danelli Tamara

Gomez Patricio Martin

Penco Sergio

Elena Marastoni

Formula (I) compounds are described: (I) where the groups are as defined in the description here below, the racemic mixtures, their individual enantiomers, their individual diastereoisomers, their mixtures, and their pharmaceutically acceptable salts. Said compounds are topoisomerase I inhibitors. 

Esters in position 20 of camptothecins

Compounds of formula (I) or (II) are described: where the groups are as defined in the description here below, the racemic mixtures, their individual enantiomers, their individual diastereoisomers, their mixtures, and their pharmaceutically acceptable salts. Said compounds are topoisomerase I inhibitors.

Camptothecins with a modified lactone ring

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Rome, Italy

Vesci Loredana