Centre National De La Recherche Scientifique

Université Paris—sud

Adisseo France Sas

Rocco, Flavio

Véronique Rosilio

Patrick Couvreur

Barbara Stella

Luigi Cattel

Flavio Rocco

Jack-Michel Renoir

Damien Preveraud

The invention concerns nanocapsules in the form of a colloidal suspension or in dry form, said nanocapsules comprising at least an active ingredient in the form of an oil, one ionic surfactant, optionally one nonionic surfactant, and one hydrophilic polymer. The invention also concerns their manufacture and their uses.

Nanocapsules, methods of manufacture and uses thereof

The use of squalenic acid or a derivative thereof in formulating at least one polar active principle with a molecular weight of 100 Da or more, in the form of nanoparticles, and pharmaceutical compositions thereof.

Nanoparticle derivatives of gemcitabine

The invention concerns a 2',2&#x2032;-difluoro-2&#x2032;-deoxycytidine derivative of general formula (I), wherein: R, Rand R, identical or different, represent independently of one another, a hydrogen atom or an at least Chydrocarbon acyl radical and of such conformation that it is capable of providing the compound of general formula (I), a compacted form in a polar solvent medium, at least one of groups R, Rand Rbeing other than a hydrogen atom.

Gemcitabine derivatives nanoparticles

Growing community of inventors

Paris, France

Véronique Rosilio