Basf Aktiengesellschaft

Knoll Aktiengesellschaft

Verena Baldinger

Liliane Unger

Manfred Raschack

Werner Seitz

Josef Gries

Klaus Ruebsamen

Dieter Lenke

Bernhard Schmied

Laszlo Szabo

Hans J Treiber

Ferdinand Dengel

Oskar Ehrmann

Klaus Ruebsmen

Hand D Lehmann

Sulfonamide derivatives of the formula I ##STR1## where R.sup.1 is a C.sub.1 -C.sub.4 -alkyl or phenyl group which may be substituted by halogen, trifluoromethyl or C.sub.1 -C.sub.4 -alkyl, R.sup.2 is hydrogen or C.sub.1 -C.sub.4 -alkyl, A is a group CHOR.sup.3 C.dbd.O, C.dbd.S or C.dbd.N--OR.sup.4, R.sup.3 is hydrogen, C.sub.1 -C.sub.4 -alkyl phenyl, benzyl or C.sub.1 -C.sub.4 -acyl, R.sup.4 is hydrogen or methyl, B may be methylene or ethylene in the m or p position or, of A is not carbonyl, may be methyleneoxy, the oxygen atom being bonded to the aromatic, and E is a carboxyl, phosphonic acid or sulfo radical, their physiologically acceptable salts, esters with C.sub.1 -C.sub.4 -alcohols or amides or the tetrazol-5-yl radical, their preparation and their use as drugs.

Sulfonamide derivatives and drugs obtained therefrom

Compounds of the formula ##STR1## where R.sup.1 to R.sup.7, m, n and p have the meanings stated in the description, and certain derivatives which are p-substituted in the left-hand phenyl ring, are useful for the treatment of disorders.

Phenylacetonitriles which are substituted by basic groups, their

Basically substituted phenylacetonitriles ##STR1## where R.sup.1 to R.sup.6 and n have the meanings stated in the description, and their preparation are described. The compounds are useful for the treatment of disorders.

Basically substituted phenylacetonitriles, their preparation and drugs

The use of (S)-emopamil and the salts thereof for the treatment of migraine is described.

(S)-emopamil for the treatment of migraine

Phenylacetaldehydes which are substituted by basic groups, of the formula ##STR1## where R.sup.1 to R.sup.8, m and n have the meanings stated in the description, and their preparation are described. The substances are useful for the treatment of disorders.

Phenylacetaldehydes substituted by basic groups, their preparation and

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Verena Baldinger