Laila Nutraceuticals

Laila Impex

Kasina Laila Innova Pharmaceuticals Private Limited

Laila Pharmaceuticals Pvt. Ltd.

Laila Nutraceurticals

P.l. Thomas-laila Nutraceuticals

Venkateswarlu Somepalli

Ganga Raju Gokaraju

Rama Raju Gokaraju

Trimurtulu Golakoti

Kiran Bhupathiraju

Venkata Kanaka Ranga Raju Gokaraju

Venkata Krishna Raju Alluri

Venkata Subbaraju Gottumukkala

Sudhakar Kasina

Venkateswara Rao Chirravuri

Krishanu Sengupta

Krishanu Senguptha

Sengupta Krishanu

Paul G Abrams

Ramchand Nanappan Chaniyilparampu

Anitha Krishnan Nair

Anuj Kapoor

Kiran Bhuphatiraju

Synergistic herbal compositions comprising combination of a first ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts ofand a second ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts offor improving testosterone levels. The invention further provides the method of obtaining at least one health benefit related to enhanced anabolic and androgenic activities in the body selected from improving testosterone levels, energy levels, sustained energy, vigor, stamina, healthy aging, cellular longevity, muscle mass, muscle strength sexual function (libido and erectile function) and psychological well-being (mood and focus); and reducing stress in humans and alleviating the symptoms associated with the low levels of testosterone in humans such as loss of libido, loss of erectile function, abdominal obesity, decreased muscle mass and strength, fatigue, mood swing, decreased bone density, decreased motivation, and decreased memory and concentration.

Synergistic herbal compositions for testosterone boosting

The invention provides to an enriched(Ashwagandha) extract composition comprising withanolide glycosides, withanolide aglycones and reduced levels of withaferin-A. The invention also provides to process for the preparation of these compositions and further provides to methods of improving testosterone levels, energy levels, sustained energy, vigor, stamina, and muscle mass and muscle strength using these compositions.

composition, method of preparation and use thereof

Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived fromandfor increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.

Compositions for improving lean body mass, brown adipose tissue and for inhibiting advanced glycation ends product

The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived fromand a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived fromfor obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprisingandand optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.

Synergistic herbal compositions for the treatment of obesity and overweight

Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived fromandfor improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived fromandand at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived fromandfor improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.

The invention discloses 4-(arylamino)selenophenopyrimidine derivatives of formula (I), hydrates, solvates, isomers, or pharmaceutically acceptable salts thereof; process for their preparation and methods of treating or inhibiting or controlling a cell proliferative disorders, particularly cancer using said compounds. Pharmaceutical compositions comprising 4-(arylamino)selenophenopyrimidine derivatives of formula (I) are useful for the treatment, inhibition, or control of cancer. 

Substituted 4-(arylamino) selenophenopyrimidine compounds and methods of use thereof

The invention relates toF-labeled compounds of formula (I), hydrates, isomers, or pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions. The invention relates to the methods of diagnosing kidney function in humans by PET imaging. 

F-18 radiolabeled compounds for diagnosing and monitoring kidney function

Selenophene compounds of formula (I) are described herein. In the compounds of Formula (I), ring A is a 6-membered aromatic fused ring, optionally containing one, two or three nitrogen atoms; a 5-membered heteroaromatic fused ring; or a mono- or bicyclic saturated heterocyclic fused ring having at least one ring member selected from the group consisting of N, O, S, SO and SO; Y in ring B is nitrogen or substituted carbon; X is NR, O, S, S(O), or S(O). R, R, R, R, and Rare defined in the specification. Selenophene compounds of formula (I) may be used in methods of treating cell proliferative disorders, particularly cancer. Pharmaceutical compositions containing selenophene compounds of formula (I) may be used for treatment, inhibition, or control of cancer. 

Substituted 4-(selenophen-2(or-3)-ylamino)pyrimidine compounds and methods of use thereof

The invention discloses a compound of formula (I) wherein, at least one of R, R, Rand Ris &#x2014;C(&#x2550;O)Rand R, RRand Rare H or CHand Ris alkyl or alkenyl group. The alkenyl group have one or more number of double bonds either in cis form or trans form or both. In R, where n is 12 to 30 carbons; and pharmaceutically acceptable salt thereof. The said alkenyl groups are preferably selected from the group consisting of eicosapentaenoic acid (EPA) or DHA (docosahexaenoic acid). This invention further discloses processes for their preparation of compounds of formula I and pharmaceutical compositions that contain these compounds. 

Orally active curcuminoid compounds

A process for producing an enriched fraction of tetrahydoxycurcumin containing, tetrahydroxycurcumin, demethylcurcumin, demethylmonodemethoxycurcumin and bisd.emethoxycurcumin and colorless tetrahydroderivatives thereof. The process consists of demethylation of natural curcumins, obtained, in turn, from the organic solvent extract of turmeric fromspecies. The said enriched fraction of tetrahydroxycurcumin is subjected to hydrogenation to get colorless tetrahydrotetrahydroxycurcumin enriched fraction. The enriched fractions of tetrahydroxycurcumin and colorless tetrahydrotetrahydroxycurcumin exhibits potent antioxidative action and reduces inflammation.

[object Object]

Synergistic anti-adipogenic and pro-lipolytic compositions for the prevention and amelioration of adipogenesis and lipolysis mediated diseases, comprising at least two extracts selected from enriched demethylated curcuminoids obtained fromand. The anti-adipogenic and pro-lipolytic compositions optionally contain one or more anti-obesic agents. These compositions are useful for preventing anti-inflammatory and free radical mediated diseases.

Synergistic phytochemical composition for the treatment of obesity

A process for the production of &#x3b3;-mangostin comprising the steps of preparing O-methyl &#x3b3;-mangostin preferably from plants, subjecting the pure or partially pure O-methylated &#x3b3;-mangostin to demethylation reaction procedure followed by purification of the said demethylated product to obtain pure &#x3b3;-mangostin.

Process for producing &#x3b3; -mangostin

Disclosed herein are novel dietary supplement compositions comprising enriched 3-O-acetyl-11-keto-&#x3b2;-boswellic acid and enriched demethylated curcuminoids, wherein the composition exhibits anti-inflammatory, antiulcerogenic and anti-oxidant activities. Also disclosed are novel compositions comprising enriched 3-O-acetyl-11-keto-&#x3b2;-boswellic acid, enriched demethylated curcuminoids that have a synergistic effect on specific inhibition of&#x2014;COX-2 and 5-LOX activity and optionally containing glucosamine, resveratrol, garlic extract, chondroitin, methlysulphonymethane, bromelain, serratiopeptidase, quercitine, gallic acid, caffeic acid, green tea extract, aspirin and ibuprofen.

Synergistic anti-inflammatory and antioxidant dietary supplement compositions

The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.

Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers

Selenopheno triazene analogs, their compositions, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts and mixtures thereof are useful for the treatment of metastatic malignant melanoma and other cancers. The selenopheno triazene analogs have the general formulae (I) or (II): wherein the substituents R, R, R, R, and Rare as described in the specification. Other cancers include which may be treated with these compounds include, but are not limited to, malignant melanoma, leukemia, lymphomas (Hodgkins and non-Hodgkins), sarcomas (Ewing's sarcoma), brain tumors, central nervous system (CNS) metastases, gliomas, carcinomas such as breast cancer, prostate cancer, lung cancer (small cell and non-small cell), colon cancer, pancreatic cancer, Head and Neck cancers and oropharyngeal squamous cell carcinoma.

Growing community of inventors

Vijayawada, India

Venkateswarlu Somepalli