Novartis Vaccines & Diagnostics, Gmbh

Chiron Corporation

Grifols Worldwide Operations Limited

Venkatakrishna Shyamala

Giulia C Kennedy

Christoph Reinhard

Joerg Kaufmann

Anne B Jefferson

Vivien W Chan

Greg Harrowe

Hong Xin

Sergio Pichuantes

Hamiduddin Khoja

Patricia Tekamp Olson

West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.

Identification of oligonucleotides for the capture, detection and quantitation of West Nile Virus

Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus

The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.

HX2004-6 polypeptide expressed in cancerous cells

Human parvovirus B19 primers and probes derived from conserved regions of the parvovirus B19 genome are disclosed. Also disclosed are nucleic acid-based assays using the primers and probes.

Diagnostic assays for parvovirus B19

A new endothelin B receptor has been identified, and the amino acid and nucleotide sequence of the receptor are provided. The nucleotide sequence is useful to construct expression cassettes and vectors to produce host cells which are capable of expressing the receptor, its mutants, fragments, or fusions. Such polypeptides are useful for identifying new endothelin agonists and antagonists.

Endothelin B.sub.1, (ETB.sub.1) receptor polypeptide and its encoding

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Oakland, CA, United States of America

Venkatakrishna Shyamala