The United States of America As Represented by the Administrator of the

Other

Detectachem, Inc.

Vaughan L Clift

Tiffany M Conerly

Richard L Pettys

Kristin L Harriman

David M Headley

Peggy A Whitson

Clarence F Sams

Kelly E McDonald

A method of rapidly detecting trace materials including biohazards, toxins, radioactive materials, and narcotics in situ is disclosed. A corresponding apparatus is disclosed. A trace of the material is collected on a pad of the card component, collected by swiping the pad on suspected surface or exposure to the suspected air volume. A novel card component is disclosed that when inserted in a chemical detection unit (CDU), releases reaction chemicals from flexible walled capsules in desired sequence. The exposed pad containing trace material and chemicals are heated in the chemical detection unit to produce a spectral pattern that is analyzed by the optical electronics in the CDU and results are displayed, stored and/or transmitted over a communications network.

System with card component and chemical detection unit for detection of trace chemicals

Method for detection of chemicals on a surface

Apparatus and techniques are provided for precise measuring and monitoring of certain vital signs of patients that have been difficult to measure especially in emergency situations. Sensor may be used for detecting contraction and expansion in the vascular bed of the lining tissue of the external auditory canal during a cardiac cycle to obtain a better indication of certain physiological parameters. Such a signal generally may be superimposed with an additional signal that is primarily due to breathing activity of the patient. Based on various scenarios different sensors may be used to determine the signal due to breathing activity and thus the physiological parameter of interest may be derived. The signal corresponding to the physiological parameter of interest, for example, blood pressure may then be used to monitor the vital signs or control other medical equipment.

Apparatus and method for precision vital signs determination

An intra aural probe for monitoring multiple physiological parameters simultaneously. The probe includes a pressure sensor, a temperature sensor and a light sensor. The probe is dimensioned to fit snugly and sealingly within the outer aural cavity. The probe measures blood pressure and pulse rate and volume of blood by detecting contraction and expansion in the vascular bed of the lining tissue of the external auditory canal during the cardiac cycle. The probe also measures respiratory rate and respiratory volume by detecting pressure changes across the tympanic membrane or movement of the tympanic membrane induced by corresponding pressure changes in the naso-pharynx and trachea during respiration. In addition, the probe measures temperature in the auditory canal, measures electroencephalographic voltages or electrocardiographic voltages by measuring small potential differences between the external auditory canal region and a suitable reference position, measures electroencephalographic currents by measuring magnetic flux, and measures changes in oxygen saturation of the haemoglobin traveling in the capillary bed lining the external auditory canal.

Intra aural integrated vital signs monitor

An apparatus and method for using the apparatus for staining particular cell markers is disclosed. The apparatus includes a flexible tube that is reversibly pinched into compartments with one or more clamps. Each compartment of the tube contains a separate reagent and is in selective fluid communication with adjoining compartments.

Whole blood cell staining device

The present invention provides a method and apparatus for separating a blood sample having a volume of up to about 20 milliliters into cellular and acellular fractions. The apparatus includes a housing divided by a fibrous filter into a blood sample collection chamber having a volume of at least about 1 milliliter and a serum sample collection chamber. The fibrous filter has a pore size of less than about 3 microns, and is coated with a mixture including between about 1-40 wt/vol % mannitol and between about 0.1-15 wt/vol % of plasma fraction protein (or an animal or vegetable equivalent thereof). The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber.

Method and apparatus for the collection, storage, and real time analysis

The present invention provides an apparatus for separating a relatively large volume of blood into cellular and acellular fractions without the need for centrifugation. The apparatus comprises a housing divided by a fibrous filter into a blood sample collection chamber having a volume of at least about 1 milliliter and a serum sample collection chamber. The fibrous filter has a pore size of less than about 3 microns, and is coated with a mixture of mannitol and plasma fraction protein (or an animal or vegetable equivalent thereof). The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber.

Growing community of inventors

Houston, TX, United States of America

Vaughan L Clift