Universitéde Montreal

Vasile Diaconu

Jocelyn Faubert

In the method and apparatus for assessing neural integrity of a patient's central nervous system, the patient is stimulated with a visual or auditory flickering stimulus, and oxygenation in the patient's second eye is sensed. Finally, the method and apparatus detects whether a change in the sensed oxygenation occurs in response to stimulation of the patient with the visual or auditory flickering stimulus. This change in the sensed oxygenation is indicative of neural integrity of the patient's central nervous system.

Flicker-induced interocular transfer-of-oxygenation for non-invasively assessing neural integrity of a patient's central nervous system

In the spectroreflectometry oxygenation measuring method and device, a light source produces a light beam having a spectral bandwidth including the wavelengths from 450 nm to 850 nm. A first optical system propagates the light beam from the light source to a two-dimensional area of the fundus of a patient's eye, the light beam being reflected at least in part by the fundus of the patient's eye to produce a reflected light beam. A detector unit detects the spectral content of the reflected light beam and produces a signal indicative of the spectral content of this reflected light beam. A second optical system propagates the reflected light beam from the fundus of the patient's eye to the detector unit. This second optical system comprises an optical scanning sub-system for scanning a plurality of points of the two-dimensional area of the fundus of the patient's eye. Finally, the optical scanning sub-system comprises optical elements for transmitting to the detector unit only a portion of the reflected light beam corresponding to the point of the two-dimensional area being scanned to thereby conduct at this point a spectroreflectometry oxygenation measurement.

On-line and real-time spectroreflectometry measurement of oxygenation in

In the spectroreflectometry oxygenation measuring method and device, a light source produces a light beam having a spectral bandwidth including the wavelengths from 450 nm to 850 nm. A first optical system propagates the light beam from the light source to the fundus of a patient's eye, the light beam being reflected at least in part by the fundus of the patient's eye to produce a reflected light beam. A detector unit detects the spectral content of the reflected light beam and produces a signal indicative of this spectral content. A second optical system propagates an axial central portion of the reflected light beam along a predetermined propagation path from the fundus of the patient's eye to the detector unit. To that effect, the second optical system comprises a mirror defining an angle of 45.degree. with the predetermined propagation path and comprising (a) an axial opening for transmitting to the detector unit only the axial central portion of the reflected light beam, and (b) a light-reflecting surface surrounding the axial opening for deviating the axial peripheral portion of the reflected light beam toward the display system. The detector unit comprises a spectrograph responsive to the axial central portion of the reflected light beam to produce a light spectrum, and an array of detectors for measuring intensities of the light components of different wavelengths of the light spectrum. The light beam from the light source has an intensity substantially equal to daylight.

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