Biota Scientific Management Pty Ltd

Van T T Nguyen

Darryl McConnell

Betty Jin

Wen-Yang Wu

Stephen E Shanahan

Simon J F MacDonald

Michael D Dowle

Andrew McM Mason

The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; Ris acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C-Calkyl Ccycloalkyl, C-Calkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.

Dimeric compounds and their use as anti-viral agents

The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; Ris acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C&#x2013;Calkyl Ccycloalkyl, C&#x2013;Calkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection 

The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; Ris acetyl or trifluoroacetyl; X is CONH, SONH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection 

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Noble Park, Australia

Van T T Nguyen