Dilon Technologies, Inc.

Biom'up France Sas

Valérie Centis

William Spotnitz

Doris Moura Campos

Alexia De Gasperis

Emmanuelle Monchaux

The invention relates to a printed hemostatic product having at least three-dimensions and being made of a stack of layers deposited on one another from a first external layer up to a second external layer, wherein adjacent layers of the stack of layers are joined together, and wherein at least one layer of the stack of layers has at least one portion made from an hemostatic flowable with a composition comprising: non-cross-linked collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen; and—at least one monosaccharide. The invention also relates to a method for forming such an hemostatic product with a three-dimensional additive printer, and the use of an hemostatic flowable as a printing ink in such a three-dimensional additive printer.

Multi-dimensional hemostatic product and method for producing the same

The invention relates to a kit to prepare an hemostatic flowable comprising: &#x2014;A hemostatic powder having a composition comprising: &#x2218;non-cross-linked collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen; &#x2218;at least one monosaccharide; and &#x2218;at least one glycosaminoglycan; &#x2014;A saline solution to be mixed with the hemostatic powder in order to form the hemostatic flowable. The invention also relates to a method for preparing an hemostatic flowable with such a kit, comprising the steps of: a. Providing the hemostatic powder in a container; b. Adding a quantity of the saline solution in the container enclosing the hemostatic powder, closing and shaking said container in order to promote hydration of the hemostatic powder to form the hemostatic flowable.

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Lyons, France

Valérie Centis