Molecular Partners Ag

Valérie Perrine Calabro

Marcel Walser

Victor Levitsky

Nicolo Rigamonti

Patrick Amstutz

Clara Domke

Niina Elisabet Veitonmäki

Pamela Anna Trail Smith

The present disclosure relates to multispecific proteins comprising designed ankyrin repeat domains with binding specificity for different targets, such as, e.g. CD40 and FAP. In addition, the present disclosure relates to nucleic acids encoding such multispecific proteins, pharmaceutical compositions comprising such multispecific proteins or nucleic acids, and the use of such binding proteins, nucleic acids or pharmaceutical compositions in methods for treating or diagnosing diseases, such as cancer, in a mammal, including a human.

Multispecific proteins

The present invention relates to recombinant binding proteins comprising one or more designed ankyrin repeat domains with binding specificity for coronavirus spike proteins, nucleic acids encoding such proteins, pharmaceutical compositions comprising such proteins or nucleic acids, and the use of such proteins, nucleic acids or pharmaceutical compositions in the treatment of coronavirus diseases, particularly diseases caused by SARS-CoV-2.

Ankyrin repeat binding proteins and their uses

Growing community of inventors

Bergdietikon, Switzerland

Valérie Perrine Calabro