Centre National De La Recherche Scientifique

Universitè De Montpellier

Universite Paris Cité

Metafora Biosystems

Assistance Publique-hopitaux De Paris

Université Paris Diderot-Paris 7

Université Montpellier 2 Sciences Et Techniques

Valérie Courgnaud

Marc Sitbon

Vincent Petit

Jean-Luc Battini

Donatella Giovannini

Jawida Lezaar

Diane Descamps

Charles-Henri Lecellier

Manuella Bouttier

Gilles Collin

Svilena Ivanova

Julien Bellis

Methods for detecting and/or measuring the level of sodium-dependent multivitamin transporter (SMVT) in a biological sample. The methods include the steps of: (a) contacting the biological sample with a PERV-B.RBD ligand, a variant and/or a fragment thereof; and, detecting and/or measuring the binding of the PERV-B.RBD ligand, variant and/or fragment thereof to SMVT.

Use of ligands derived from receptor-binding domain of porcine endogenous retrovirus type B for diagnosing SMVT-related diseases

Disclosed are methods for diagnosing CAT1-related diseases, wherein the methods include detecting CAT1 in a cell by a BLV.RBD ligand, or a variant or a fragment thereof. Also disclosed is a BLV.RBD ligand, or a variant or a fragment thereof for use in the treatment of CAT1-related diseases and/or BLV infections.

Use of receptor-binding domain derived from bovine leukemia virus for the diagnosis or treatment of cationic l-amino acid transporter-related diseases

The invention relates to an in vitro method for identifying microRNAs or the target mRNAs thereof, the expression of which during the infection of cells by a virus using a cell receptor and at least one cell co-receptor for entering the cell, is specifically modified on the basis of the cell co-receptor used by the virus for its entering the cells, comprising:

Identifying viral cell tropism

Growing community of inventors

Montpellier, France

Valérie Courgnaud