Zambon Group S.p.a.

Valeriano Merli

Giorgio Sagramora

Claudio Giordano

Giorgio Soriato

Vincenzo Cannata

Dario Tentorio

Roberto Casagrande

Claudio Dal Santo

Placido Bertin

A process for the preparation and purification of L-5-(2-hydroxypropionylamino)-2,4,6-triiodoisophthalic acid bis-(1,3-dihydroxypropylamide) by using ion-exchange resins is described.

Process for the preparation and purification of iodinated contrast agents

A process of spontaneous resolution of compounds of formula ##STR1## wherein R has the meanings reported in the description, is described. The compounds of formula III are intermediates useful for the preparation of Diltiazem.

Resolution process of intermediates useful for the preparation of

A process for the preparation of (2S,3S)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propioni c acid by resolution of the racemic mixture is described. The resolution is carried out by using as resolving agent (1S,2S)-threo-1-phenyl-2-amino-1,3-propanediol or (1S,2S)-threo-1-(4-methylthiophenyl)-2-amino-1,3-propanediol.

Process for the preparation of intermediates for the synthesis of

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Occhiobello, Italy

Valeriano Merli