The Feinstein Institutes for Medical Research

Valentin A Pavlov

Kevin J Tracey

Sangeeta S Chavan

Adam M Kressel

Methods for electrical modulation of inflammation or serum TNF levels in a subject.

Treatment of inflammation by selective DMV cholinergic neuron stimulation

A method of treating a fatty liver disease in a subject. The method comprises administering to the subject an effective amount of a cholinergic pathway stimulating agent, wherein the fatty liver disease is selected from non-alcoholic fatty liver (NAFL), alcoholic fatty liver (AFL), non-alcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), NASH-associated liver fibrosis, ASH-associated liver fibrosis, non-alcoholic cirrhosis, and alcoholic cirrhosis.

Methods of treatment of fatty liver disease by pharmacological activation of cholinergic pathways

A method of treating a subject with a cytokine-mediated inflammatory disorder comprising administering to the subject an effective amount of a pharmaceutically acceptable cholinesterase inhibitor, provided that the inhibitor is not galantamine.

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Bayside, NY, United States of America

Valentin A Pavlov